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Table 1 Patient characteristics and nature of the reported ADEs

From: Construct and concurrent validity of a patient-reported adverse drug event questionnaire: a cross-sectional study

Characteristic N (%)
Patients 135
Women 47 (35)
Mean age in years (SD) 64 (9)
Education  
  Lowa 34 (25)
  Middleb 53 (39)
  Highc 39 (29)
  Other 9 (7)
Number of prescribed oral glucose-lowering drugsd  
  1 oral glucose-lowering drug 91 (68)
  2 oral glucose-lowering drugs 38 (29)
  3 oral glucose-lowering drugs 4 (3)
Classes of prescribed oral glucose-lowering drugsd  
  Biguanides 125 (94)
  Dipeptidyl peptidase 4 (DPP-4) inhibitors 4 (3)
  Glucagon-like peptide-1 (GLP-1) 5 (4)
  Sulfonamides 42 (32)
  Thiazolidinediones 3 (2)
Median number of systemic drugs prescribed (IQR) 7 (5–9)
Patients additionally on insulin 24 (18)
Patients reporting an ADE 37 (27)
Number of ADEs reported (range) 146 (1–11)
First time experiencing the ADE  
  Today 6 (4)
  Yesterday 1 (1)
  2-7 days ago 5 (3)
  Between 1 week and 1 month ago 14 (10)
  Between 1 and 6 months ago 14 (10)
  Between 6 and 12 months ago 21 (14)
  More than 12 months ago 85 (58)
ADE gone away or improved  
  Not yet 120 (82)
  Clearly improved 14 (10)
  ADE was treated and has improved 4 (3)
  ADE went away by itself 0 (0)
  ADE went away after quitting medication 1 (1)
  ADE went away after treatment 1 (1)
  Other 6 (4)
How much bothersome  
  Not at all 11 (8)
  Only a bit 22 (15)
  Somewhat 71 (49)
  Quite a lot 31 (21)
  Very much 11 (8)
Influence daily functioning  
  None 47 (32)
  Only a bit 24 (17)
  Somewhat 54 (37)
  Quite a lot 18 (12)
  Very much 2 (1)
  1. ADEs = Adverse drug events; SD = Standard deviation; IQR = Interquartile range.
  2. aNo education; elementary school; junior secondary vocational education.
  3. bJunior general secondary education; senior secondary vocational education.
  4. cSenior general secondary education; higher professional education; university education.
  5. dMedication use is based on 133 patients since drug information of 2 patients was not available.