Table 1 Patient characteristics and nature of the reported ADEs
Characteristic | N (%) |
|---|---|
Patients | 135 |
Women | 47 (35) |
Mean age in years (SD) | 64 (9) |
Education | Â |
  Lowa | 34 (25) |
  Middleb | 53 (39) |
  Highc | 39 (29) |
  Other | 9 (7) |
Number of prescribed oral glucose-lowering drugsd | Â |
  1 oral glucose-lowering drug | 91 (68) |
  2 oral glucose-lowering drugs | 38 (29) |
  3 oral glucose-lowering drugs | 4 (3) |
Classes of prescribed oral glucose-lowering drugsd | Â |
  Biguanides | 125 (94) |
  Dipeptidyl peptidase 4 (DPP-4) inhibitors | 4 (3) |
  Glucagon-like peptide-1 (GLP-1) | 5 (4) |
  Sulfonamides | 42 (32) |
  Thiazolidinediones | 3 (2) |
Median number of systemic drugs prescribed (IQR) | 7 (5–9) |
Patients additionally on insulin | 24 (18) |
Patients reporting an ADE | 37 (27) |
Number of ADEs reported (range) | 146 (1–11) |
First time experiencing the ADE | Â |
  Today | 6 (4) |
  Yesterday | 1 (1) |
  2-7 days ago | 5 (3) |
  Between 1 week and 1 month ago | 14 (10) |
  Between 1 and 6 months ago | 14 (10) |
  Between 6 and 12 months ago | 21 (14) |
  More than 12 months ago | 85 (58) |
ADE gone away or improved | Â |
  Not yet | 120 (82) |
  Clearly improved | 14 (10) |
  ADE was treated and has improved | 4 (3) |
  ADE went away by itself | 0 (0) |
  ADE went away after quitting medication | 1 (1) |
  ADE went away after treatment | 1 (1) |
  Other | 6 (4) |
How much bothersome | Â |
  Not at all | 11 (8) |
  Only a bit | 22 (15) |
  Somewhat | 71 (49) |
  Quite a lot | 31 (21) |
  Very much | 11 (8) |
Influence daily functioning | Â |
  None | 47 (32) |
  Only a bit | 24 (17) |
  Somewhat | 54 (37) |
  Quite a lot | 18 (12) |
  Very much | 2 (1) |