Skip to main content

Table 2 Patient-reported signs and symptoms of CRPC

From: Pain in castration-resistant prostate cancer with bone metastases: a qualitative study

Concept Round I Round II Concept Frequency (%)
  PT 01 PT 02 PT 03 PT 04 PT 05 PT 06 PT 07 PT 08 PT 09 PT 10 PT 11 PT 12 PT 13 PT 14 PT 15 PT 16 PT 17  
Bone Pain   X X X X X X X X X X X X X X X X 16 (94)
   BTcP (incident)     X   X    X     X   X    5 (29)
   BTcP (idiopathic)           X X   X     X 4 (24)
   BTcP ("end-of-dose failure")    X X   X    X   X X      X 7 (41)
Skeletal-related events (fractures)   X        X          2 (12)
Fatigue X   X   X X   X X X X        8 (47)
Low energy X X   X   X X X   X         7 (41)
Loss of strength   X      X       X      3 (18)
Urinary dysfunction X X   X X X X X X X X X      X 12 (71)
   Blood in urine        X    X   X       3 (18)
   Can't empty bladder     X    X            2 (12)
   Increased urinary frequency during the day   X   X   X            X 4 (24)
   Difficulty starting urination     X    X     X        3 (18)
   Urinary incontinence     X    X   X   X        4 (24)
   Weak or interrupted flow of urine     X X   X   X          4 (24)
   Increased urinary frequency during the night X    X   X             3 (18)
   Painful or burning urination        X X           2 (12)
   Poor stream     X X              2 (12)
Erectile dysfunction          X     X      2 (12)
Fever/sweats/chills   X X     X X      X    X   6 (35)
Numbness/loss of sensation       X X X        X    4 (24)
Altered taste perception X               X    2 (12)
Loss of appetite       X      X     X    3 (18)
Weight loss X         X   X        3 (18)
Weight gain   X     X             2 (12)
Gastrointestinal disturbance    X X X X X   X   X        7 (41)
   Bloating     X   X             2 (12)
   Constipation     X X X      X        4 (24)
   Diarrhea    X    X             2 (12)
   Nausea/vomiting     X   X X   X   X        5 (29)
Anxiety     X        X        2 (12)
Depression     X    X     X   X      4 (24)
  1. Note: X indicates the first time that the respective concept was elicited by a participant.