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Table 2 Patient-reported signs and symptoms of CRPC

From: Pain in castration-resistant prostate cancer with bone metastases: a qualitative study

Concept

Round I

Round II

Concept Frequency (%)

 

PT 01

PT 02

PT 03

PT 04

PT 05

PT 06

PT 07

PT 08

PT 09

PT 10

PT 11

PT 12

PT 13

PT 14

PT 15

PT 16

PT 17

 

Bone Pain

 

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

16 (94)

   BTcP (incident)

   

X

 

X

  

X

   

X

 

X

  

5 (29)

   BTcP (idiopathic)

         

X

X

 

X

   

X

4 (24)

   BTcP ("end-of-dose failure")

  

X

X

 

X

  

X

 

X

X

    

X

7 (41)

Skeletal-related events (fractures)

 

X

      

X

        

2 (12)

Fatigue

X

 

X

 

X

X

 

X

X

X

X

      

8 (47)

Low energy

X

X

 

X

 

X

X

X

 

X

       

7 (41)

Loss of strength

 

X

    

X

     

X

    

3 (18)

Urinary dysfunction

X

X

 

X

X

X

X

X

X

X

X

X

    

X

12 (71)

   Blood in urine

      

X

  

X

 

X

     

3 (18)

   Can't empty bladder

   

X

  

X

          

2 (12)

   Increased urinary frequency during the day

 

X

 

X

 

X

          

X

4 (24)

   Difficulty starting urination

   

X

  

X

   

X

      

3 (18)

   Urinary incontinence

   

X

  

X

 

X

 

X

      

4 (24)

   Weak or interrupted flow of urine

   

X

X

 

X

 

X

        

4 (24)

   Increased urinary frequency during the night

X

  

X

 

X

           

3 (18)

   Painful or burning urination

      

X

X

         

2 (12)

   Poor stream

   

X

X

            

2 (12)

Erectile dysfunction

        

X

   

X

    

2 (12)

Fever/sweats/chills

 

X

X

   

X

X

    

X

  

X

 

6 (35)

Numbness/loss of sensation

     

X

X

X

      

X

  

4 (24)

Altered taste perception

X

             

X

  

2 (12)

Loss of appetite

     

X

    

X

   

X

  

3 (18)

Weight loss

X

       

X

 

X

      

3 (18)

Weight gain

 

X

   

X

           

2 (12)

Gastrointestinal disturbance

  

X

X

X

X

X

 

X

 

X

      

7 (41)

   Bloating

   

X

 

X

           

2 (12)

   Constipation

   

X

X

X

    

X

      

4 (24)

   Diarrhea

  

X

  

X

           

2 (12)

   Nausea/vomiting

   

X

 

X

X

 

X

 

X

      

5 (29)

Anxiety

   

X

      

X

      

2 (12)

Depression

   

X

  

X

   

X

 

X

    

4 (24)

  1. Note: X indicates the first time that the respective concept was elicited by a participant.
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Health and Quality of Life Outcomes

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