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Table 2 Clinical Characteristics and Treatment Patterns, Overall and by Fibromyalgia Severity Level

From: The comparative burden of mild, moderate and severe Fibromyalgia: results from a cross-sectional survey in the United States

   Severity Level
Characteristic Overall
(n = 203)
Mild
(n = 21)
Moderate
(n = 49)
Severe
(n = 133)
p-value a
Time since first experienced FM symptoms, years      0.684
   mean (SD) 10.7 (8.1) 10.8 (6.3) 10.1 (8.1) 10.9 (8.3)  
   median (range) 9.0 (0.0 - 48.0) 10.0 (3.0 - 23.0) 9.0 (1.0 - 32.0) 9.0 (0.0 - 48.0)  
Time since diagnosis, years      
   mean (SD) 6.9 (6.5) 7.4 (6.1) 6.2 (6.2) 7.0 (6.6) 0.604
   median (range) 6.0 (0.0 - 48.0) 6.0 (0.0 - 22.0) 4.0 (0.0 - 30.0) 6.0 (0.0 - 48.0)  
Time since first prescription for FM, years      0.670
   mean (SD) 6.3 (6.2) 7.2 (6.6) 5.9 (6.6) 6.2 (6.0)  
   median (range) 4.5 (0.0 - 30.0) 5.0 (0.0 - 22.0) 3.0 (0.0 - 30.0) 5.0 (0.0 - 21.0)  
Number of positive MTPS points      0.036
   mean (SD) 14.7 (3.4) 13.7 (4.1) 13.8 (3.8) 15.2 (3.0)  
   median (range) 16.0 (4.0 - 18.0) 16.0 (5.0 - 18.0) 15.0 (4.0 -18.0) 16.0 (4.0 - 18.0)  
Number of comorbid conditionsb      0.112
   mean (SD) 4.2 (2.4) 2.9 (1.6) 4.1 (2.3) 4.4 (2.6)  
   median (range) 4.0 (1.0-10.0) 3.0 (1.0-7.0) 4 (1.0-10.0) 4.0 (1.0-10.0)  
Average pain intensity, n (%)      < 0.001
   Mild (0-3) 20 (9.9) 12 (57.1) 7 (14.3) 1 (0.8)  
   Moderate (4-6) 74 (36.6) 6 (28.6) 24 (49.0) 44 (33.3)  
   Severe (7-10) 108 (53.5) 3 (14.3) 18 (36.7) 87 (65.9)  
Number of physician visits (per year)      < 0.001
   mean (SD) 16.9 (17.9) 9.7 (11.3) 11.6 (11.2) 19.9 (19.9)  
   median (range) 12.0 (4.0 - 132.0) 4.0 (4.0 - 48.0) 8.0 (4.0 - 52.0) 16.0 (4.0 - 132.0)  
Number of medications over the past 3 months, n (%)      
   ≥ 1 medication 37 (91.6) 19 (90.5) 43 (87.8) 124 (93.2) 0.487
   ≥ 3 medications 48 (47.3) 3 (14.3) 22 (44.9) 71 (53.4) 0.004
  1. a Chi-square test or the Kruskal-Wallis test, as appropriate
  2. b Among subjects with at least one comorbid condition (n = 190 overall; n = 15 mild; n = 47 moderate; n = 128 severe)
  3. Source: Clinical CRF.