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Table 4 Bootstrap Multivariate HRs for Baseline QoL Measures

From: Can changes in health related quality of life scores predict survival in stages III and IV colorectal cancer?

Baseline Variable HR (95% CI) P
General Quality of Life   
Global 0.93 (0.87 - 0.98) 0.01*
General Function   
Physical 1.08 (0.97 - 1.22) 0.16
Role Not used  
Emotional 1.01 (0.92 - 1.10) 0.86
Cognitive 1.02 (0.93 - 1.13) 0.57
Social 0.93 (0.83 - 1.02) 0.14
General Symptom   
Fatigue 1.01 (0.90 - 1.10) 0.87
Nausea/Vomiting 0.95 (0.83 - 1.05) 0.30
Pain 1.02 (0.95 - 1.09) 0.69
Dyspnea 1.05 (0.99 - 1.13) 0.14
Insomnia 1.04 (0.99 - 1.12) 0.19
Appetite Loss 1.07 (1.0 - 1.16) 0.06
Constipation 0.94 (0.85 - 1.01) 0.08
Diarrhea 1.01 (0.94 - 1.09) 0.73
Financial 0.98 (0.91 - 1.05) 0.48
  1. • HRs correspond to a 10-point increment for QoL scores
  2. • 2 sets of multivariate models were constructed: one for global QoL and other for all general function and symptom variables combined
  3. • Multivariate model (for general function and symptom variables combined) adjusted for age, gender, stage at diagnosis, prior treatment history and all baseline QoL variables excepting role function
  4. • Multivariate model for global QoL adjusted for age, gender, stage at diagnosis and prior treatment history
  5. • *P < 0.05