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Table 4 Bootstrap Multivariate HRs for Baseline QoL Measures

From: Can changes in health related quality of life scores predict survival in stages III and IV colorectal cancer?

Baseline Variable

HR (95% CI)

P

General Quality of Life

  

Global

0.93 (0.87 - 0.98)

0.01*

General Function

  

Physical

1.08 (0.97 - 1.22)

0.16

Role

Not used

 

Emotional

1.01 (0.92 - 1.10)

0.86

Cognitive

1.02 (0.93 - 1.13)

0.57

Social

0.93 (0.83 - 1.02)

0.14

General Symptom

  

Fatigue

1.01 (0.90 - 1.10)

0.87

Nausea/Vomiting

0.95 (0.83 - 1.05)

0.30

Pain

1.02 (0.95 - 1.09)

0.69

Dyspnea

1.05 (0.99 - 1.13)

0.14

Insomnia

1.04 (0.99 - 1.12)

0.19

Appetite Loss

1.07 (1.0 - 1.16)

0.06

Constipation

0.94 (0.85 - 1.01)

0.08

Diarrhea

1.01 (0.94 - 1.09)

0.73

Financial

0.98 (0.91 - 1.05)

0.48

  1. • HRs correspond to a 10-point increment for QoL scores
  2. • 2 sets of multivariate models were constructed: one for global QoL and other for all general function and symptom variables combined
  3. • Multivariate model (for general function and symptom variables combined) adjusted for age, gender, stage at diagnosis, prior treatment history and all baseline QoL variables excepting role function
  4. • Multivariate model for global QoL adjusted for age, gender, stage at diagnosis and prior treatment history
  5. • *P < 0.05