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Table 2 Disease Characteristics (N = 102)

From: Retrospective study of the effect of disease progression on patient reported outcomes in HER-2 negative metastatic breast cancer patients

Variable

N (%)

Stage at Diagnosis

 

   Stage I

12 (11.8%)

   Stage II

33 ( 32.4%)

   Stage III

20 ( 19.6%)

   Stage IV

26 (25.5%)

   Unknown

11 (10.8%)

ER Positive

76 (74.5%)

PR Positive

55 (53.9%)

ECOG PS

 

   < 2

34 (33.3%)

   = 2

6 ( 5.9%)

   > 2

3 (3.0%)

   Unknown

59 ( 57.8%)

# Months from initial dx to metastasis (Mean, SD)

37.9 (42.3)

# Months from metastasis to first progression (Mean, SD) a

13.9 (14.8)

Had second disease progression

78 (76.5%)

# Months from 1st to 2nd progression (Mean, SD)

6.6 (5.4)

Deceased Per Medical Record

45 (44.1%)

Metastatic Sites

At initial Metastatic Diagnosis

At First progression

   Bone

61 (59.8%)

67 (65.7%)

   Brain

0 (0.0%)

2 (2.0%)

   Liver

27 (26.5%)

34 (33.3%)

   Lung

29 (28.4%)

36 (35.3%)

   Peritoneum

6 (5.9%)

6 (5.9%)

   Other

35 (34.3%)

44 (43.1%)

Comorbidities Present (N,%)

 

   Hypertension

49 (48%)

   CHF

2 (2.0%)

   History of MI or Stroke

4 (3.9%)

   Other CVD

26 (25.5%)

   Diabetes

18 (17.6%)

  1. aMedian time from metastases to disease progression = 8.8 months