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Table 2 Risk factors associated with mortality at 3 months

From: Predictors of mortality and short-term physical and cognitive dependence in critically ill persons 75 years and older: a prospective cohort study

Characteristics

Alive

(n= 38)

Dead

(n= 61)

Univariate analysis

P value

Odd Ratio [95% CI]

Multivariate analysis

P

value Odd Ratio [95% CI]

ICU admission (n = 99)

Age

78.8 ± 3.1

79.7 ± 3.3

p = 0.18

1.09 [0.96-1.24]

 

Male (%)

24(63.1%)

41(68.3%)

p = 0.68

1.20 [0.51-2.80]

 

BMI, mean ± SD

28.3 ± 4.8

26.3 ± 6.5

p = 0.4

0.96 [0.88-1.05]

 

Charlson index, median (IQR)

5(4-6)

7(5-8)

p = 0.003

1.45 [1.12-1.87]

p = 0.0025

1.6 [1.2-2.2]

ADL index, mean ± SD

5.4 ± 1.

5.5 ± 1.1

p = 0.36

1.31 [0.91-1.86]

 

Cognitive score, mean ± SD

1.6 ± 1.3

1.0 ± 1.4

p = 0.03

0.73 [0.53-0.99]

 

SAPS II score, median (IQR)

49(39-63)

55(41-70)

p = 0.16

1.01[0.99-1.04]

 

APACHE II score, median (IQR)

24(16-28)

24(20-31)

p = 0.18

1.03 [0.99-1.08]

 

SOFA score, median (IQR)

6(3-8)

7(5-11)

p = 0.035

1.13 [1.01-1.27

 

Organ failures, mean ± SD

1 ± 1.1

1.7 ± 1.1

p = 0.003

1.77 [1.20-2.61]

p = 0.02

2.5 [1.15-5.2]

Mechanical ventilation, n (%)

20(52.6%)

42(68.9)

p = 0.16

0.5 [0.2-1.3]

 

NIV, n (%)

14(36.8%)

17(27.9%)

p = 0.47

1.51 [0.58-3.95]

 

Shock, n (%)

12(31.6%)

29(47.5%)

p = 0.18

1.96 [0.84-4.59]

 

Extra-renal support, n (%)

2(5.2%)

10(16.3%)

p = 0.12

0.28 [0.04-1.53]

 
  1. BMI, body mass index; ADL, Activity of Daily Living; SAPS II score, Simplified Acute Physiologic Score II, APACHE II score, Acute Physiology and Chronic Health Evaluation; SOFA score, Sequential Organ Failure Assessment; NIV, non invasive ventilation; MV, mechanical ventilation.