Predictors of health status do not change over three-year periods and exacerbation makes difference in chronic obstructive pulmonary disease

Table 1 Characteristics of COPD patients followed-up over a three-year period

Variables	Initial Assessment (n = 95)	Final Assessment (n = 95)	p-value
FEV₁ (%)	59.3 ± 23.2	58.5 ± 22.7	0.228
FEV₁ (L)	1.4 ± 0.6	1.3 ± 0.5	< 0.001
FVC (%)	90.8 ± 23.8	88.9 ± 24.7	0.167
FVC (L)	2.7 ± 0.8	2.5 ± 0.8	0.004
FEV₁/FVC	52.2 ± 11.7	51.3 ± 10.4	0.123
BMI (kg/m²)	25.9 ± 5.8	25.8 ± 5.6	0.382
SpO₂ (%)	93.6 ± 3.1	92.0 ± 4.8	< 0.001
MMRC (score)	1.5 ± 1.0	1.9 ± 1.1	0.002
6MWD (m)	437.7 ± 85.6	412. 4 ± 100.0	0.001
Charlson index (score)	3.5 ± 1.5	3.9 ± 1.4	0.009
BODE index (score)	2.2 ± 1.8	2.6 ± 2.3	0.008

Paired t-test or Wilcoxon. Values are presented as mean ± SD or as median (25-75% interquartile range). FEV₁: forced expiratory volume in the first second (% of predicted); FVC: forced vital capacity (% of predicted); BMI: body mass index; SpO₂: pulse oximetry; MMRC: Modified Medical Research Council; 6MWD: six-minute walking distance; p < 0.05.

ISSN: 1477-7525