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Table 1 Comparison of Item framework, feature, wording and supporting quotes

From: Development of a patient reported outcome measure for fatigue in motor neurone disease: the Neurological Fatigue Index (NFI-MND)

Framework

Feature

Example item

Supporting quote

Motor features

Can develop weakness

Sometimes, I lose my body strength

I have lost the ability to sustain [my strength]

Cognitive features

Concentrate on simple tasks

Sometimes, I have to concentrate on what are usually simple things

When reading a magazine or something and I'm getting tired then I find it more difficult to concentrate, it's just more difficult when I'm tired.

Motivation

Thought puts off doing

The thought of having to do something often puts me off doing it

[Because of] what's happened to get the fatigue you are less likely to want to do the same things anyway.

Tiredness

Tiredness

By the end of the day, I'm shattered

Just tiredness, all the time tiredness

Cadence

Carry over

If I've overdone things, I know about it the next day

I try not to do too much, because that'd knacker me up for the next day then

Precipitating/aggravating factors

Physical exertion induces weakness

I soon become weak after physical effort

[I get fatigued] when doing anything physical, it's surprising that the things I never used to regard as physical are now physical and causing fatigue.

Relieving factors

day rest restorative

Resting allows me to carry on

[I'd rest for] maybe three to four minutes, something like that. I make sure that it is long enough if it's any shorter then I'm back to square one; it feels like I am not recharged enough.

Severity

weak at rest

I can become weak even if I've not been doing anything

Now you just do very minimal things that you wouldn't consider as anything and you feel fatigued

Associated features

Unrefreshing nocturnal sleep

When I wake in the morning, I get the weariness feeling

I wake up in the morning, and get this weariness feeling