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Table 1 General anxiety, depression (HADS), and physical health (PCS) in individuals with familial Long QT syndrome (LQTS) and Hypertrophic cardiomyopathy (HCM) as compared to expected scores of general population.

From: General anxiety, depression, and physical health in relation to symptoms of heart-focused anxiety-a cross sectional study among patients living with the risk of serious arrhythmias and sudden cardiac death

Patient-reported outcomes

 

n

Study sample

Norwegian

expected scores*

p-value

HADS-

Total sample

125

4.9 (4.0)

3.8 (0.5)

<0.01

Anxiety

   At genetic risk

93

4.9 (3.8)

3.9 (0.5)

0.01

(0-21)

   With clinical diagnosis

32

5.0 (4.5)

3.7 (0.5)

0.10

HADS-

Total sample

125

3.1 (3.7)

2.9 (0.7)

0.50

Depression

   At genetic risk

93

3.0 (3.8)

2.9 (0.7)

0.65

(0-21)

   With clinical diagnosis

32

3.4 (3.7)

3.0 (0.8)

0.58

SF36-

Total sample

120

50.6 (8.6)

50.0 (10)

0.48

Physical health

   At genetic risk

89

52.3 (7.2)

50.0 (10)

<0.01

Summary

(0-100)

   With clinical diagnosis

31

45.5 (10.4)

50.0 (10)

0.02

  1. HADS: Hospital Anxiety and Depression Scale; PCS: SF-36 Physical Component Summary; results are presented as mean (standard deviation), number of participants and p-values.
  2. *Expected scores, based on Norwegian general population, adjusted to the age, gender, education level, and smoking habits distribution in the sample (n = 125)