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Table 4 Summary of effect of depression predicting likelihood of RTW post-MI at 6-8 and 12-13 months

From: Depression as a predictor of work resumption following myocardial infarction (MI): a review of recent research evidence

Author Finding Ratio Depression
severity
Estimate
of
relative risk
CI (95%) P value Variables included
in multivariate
analysis**
(bold indicates
significance)
DEPRESSION SIGNIFICANTLY PREDICTED RTW
6-8 MONTHS        
Fukuoka
(2009)[28]
As a time-dependent
covariate, increases in
depression score
predicted slower RTW
at 6 months
Adjusted
Hazard
ratio*
Moderate
depression
Severe
depression
0.47
0.37
0.31-0.72
0.21-0.66
< 0.001
0.001
Age, sex, nationality,
education, income, marital
status, smoking, hyperlipidemia,
Duke activity index score
(physical functioning),
job strain,
job satisfaction,
job security,
working hours
per week, shift work,
social support (from
supervisor, co-workers)
Samkange-Zeeb
(2006)[29]
Level of depression
was significant
predictor of RTW
at 6 months
Adjusted
Odds ratio
Borderline
depression
Clinical
depression
0.62
0.28
0.35-1.12
0.14-0.58
  Age, sex, profession,
anxiety, expectations
about work incapacity
and desire to RTW
Soejima
(1999)[31]
Depressed patients
less likely to
RTW at 8 months
Adjusted
Odds ratio
  0.15 0.02-0.87 < 0.031 Age, education,
occupation, personality
type health locus
of control
12-13 MONTHS        
McGee
(2006)[35]
Baseline depression
significantly predicted
RTW at 12 months
Adjusted
Odds ratio
HADS depression 0.2 0.06-0.6 0.007 Prior ACS,
age and sex
Sykes
(2000)[32]
Depression significant
predictor of RTW
at 12 months
Wald test   7.335 (df = 1)   0.0068 Decision latitude,
work social
interaction,
age, medical prognosis
(Coronary Prognostic Index)
Samkange-Zeeb (2006)[29] Level of depression
was significant
predictor of RTW
at 12 months
Adjusted
Odds ratio
Borderline
depression
Clinical
depression
0.35
0.24
0.18-0.68
0.11-0.49
  Age, sex,
profession,
anxiety,
expectations about
work incapacity
and desire to RTW
Soderman
(2003) [5]
Clinical depression
(BDI >16) predicted
RTW at 12 months
Adjusted
Odds ratio
Clinical
depression
Mild
depression
Clinical
depression
Mild
depression
9.43 (fulltime)
2.89 (fulltime)
5.44 (reduced hours)
OR not
shown
3.15-28.21
1.08-7.70
1.60-18.53
<0.001
0.0300
<0.0068
0.7848
Gender, age,
education,
exercise capacity
Bhattacharyya
(2007) [14]
Every increase in
BDI index reduced
likelihood of RTW
at 12-13 months
Adjusted
Odds ratio
  0.90 0.82-0.99 0.032 Age, gender, risk
of cardiac event,
heart failure,
antidepressant use,
Arrhythmia during
admission, recurrent
cardiac events
DEPRESSION DID NOT SIGNIFICANTLY PREDICT RTW    
6-12 MONTHS Significant
predictors
   
Brink [30] Somatic health better
predictor of RTW than
mental health at 6 months
Adjusted
Odds ratio
Physical
health
component
score
Footsteps
per day
1.08
1.18
1.02-1.14
1.01-1.38
0.011
0.033
Physical health,
age, footsteps
per day
Ladwig
(1994) [34]
Depression as a
significant predictor
of RTW at 6 months
(OR: 0.39, Cl 0.18-0.88),
was lost after adjustment
for age, social class,
rehabilitation, recurrent
infarction, cardiac events,
helplessness (OR: 0.54 CI 0.22-1.31)
  -     
Mayou (2000) [9] No significant
differences in RTW
between distressed
and nondistressed
at 12 months
  -     
Engblom [27] At 12 months,
patients' expectations
of work, duration of
absence from work
before CABS and physical
capacity of patients after
surgery are important
determinants of
RTW after CABS
Adjusted
Odds ratio
Self assessed work
capacity at six
months (Good vs Poor)
Functional Class
(Canadian CVD class
I vs II-III)
Patient expectation
about work
(RTW vs retire)
Absence from work
before the CABS
(3 months or less)
8.5
6.7
6.4
4.9
2.3-32.0
1.8-24.5
1.6-26.0
1.2-20.2
0.003
0.006
0.013
0.032
Type of rehabilitation,
previous MI, expectations
regarding work,
physical strain of work,
duration of the
preoperative absence
from work, basic
education, professional
education, socioeconomic
status, preoperative BDI
score, final work load at
exercise test, functional
class, patients' perception
of working capacity at
6 months after the CABS.
Mittag [33] Three variables predicted
RTW at 12 months in 85%
of all cases: (1) age,
(2) patients' feelings
about disability
(3) physicians' views on
the extent to which
vocationally disabled
Adjusted
Odds ratio
Age
Self perceived
disability
Physician's view of
disability
1.22
3.02
1.61
1.10-1.34
2.48-3.57
1.16-2.07
<0.01
<0.001
<0.05
Results of exercise testing,
optimistic coping style,
family income, negative
incentives for RTW, physicians'
subjective prognosis as to
re-employment, patients' wish
to return to work, age,
self perceived vocational
disability, physician's
perception of patient disability.