From: Psychometric validation of the Dutch translation of the quality of life in reflux and dyspepsia (QOLRAD) questionnaire in patients with gastroesophageal reflux disease
QOLRAD domain
Effect size*
Standardized response mean
Emotional distress
1.38
1.45
Sleep disturbance
1.40
1.41
Food/drink problems
1.93
1.86
Physical/social functioning
1.15
1.17
Vitality
1.74
1.76