Skip to main content

Table 5 Sensitivity to change

From: Health-related quality of life in patients with severe COPD hospitalized for exacerbations - comparing EQ-5D, SF-12 and SGRQ

Instrument n Admission Discharge sdiff p-value
   mean (sd) mean (sd)   
EQ-5D 106 0.60 (0.26) 0.79 (0.21) 0.69 <0.001
VAS 120 39 (14) 55 (17) 1.17 <0.001
SF-12 - SF-6D 68 0.56 (0.11) 0.59 (0.09) 0.27 0.008
SF-12 - PCS 49 28 (6) 32 (6) 0.75 <0.001
SF-12 - MCS 49 41 (11) 42 (11) 0.13 0.308
SGRQ - total 111 71 (12) 65 (14) 0.50 <0.001
SGRQ - symptoms 118 75 (17) 71 (17) 0.23 <0.001
SGRQ - activity 116 86 (12) 81 (15) 0.37 <0.001
SGRQ - impact 116 61 (15) 53 (19) 0.48 <0.001
  1. MCS: mental component score; PCS: physical component score; sdiff: standardized difference.