Health-related quality of life in patients with severe COPD hospitalized for exacerbations - comparing EQ-5D, SF-12 and SGRQ

Table 5 Sensitivity to change

Instrument	n	Admission		Discharge		sdiff	p-value
		mean	(sd)	mean	(sd)
EQ-5D	106	0.60	(0.26)	0.79	(0.21)	0.69	<0.001
VAS	120	39	(14)	55	(17)	1.17	<0.001
SF-12 - SF-6D	68	0.56	(0.11)	0.59	(0.09)	0.27	0.008
SF-12 - PCS	49	28	(6)	32	(6)	0.75	<0.001
SF-12 - MCS	49	41	(11)	42	(11)	0.13	0.308
SGRQ - total	111	71	(12)	65	(14)	0.50	<0.001
SGRQ - symptoms	118	75	(17)	71	(17)	0.23	<0.001
SGRQ - activity	116	86	(12)	81	(15)	0.37	<0.001
SGRQ - impact	116	61	(15)	53	(19)	0.48	<0.001

MCS: mental component score; PCS: physical component score; sdiff: standardized difference.

ISSN: 1477-7525