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Table 2 Comparison of the evaluation and validation sample characteristics.

From: Development of a patient reported outcome scale for fatigue in multiple sclerosis: The Neurological Fatigue Index (NFI-MS)

 

Characteristic

Evaluation sample

Validation sample

Difference between evaluation and validating sample

 

number of subjects

317

318

 
 

mean age (SD, min.—max.)(yrs)

46.8 (11.3)

46.4 (10.6)

t-test p = 0.606

 

number female (%)

234 (73.8)

217 (68.2)

chi-square p = 0.144

 

mean disease duration (SD, min.—max.)(yrs)

16.0 (9.7, 2—49)

14.2 (9.4, 2—45)

t-test p = 0.064

disease type, n (%)

pp

25 (7.9)

29 (9.1)

chi-square p = 0.932

 

rr

169 (53.3)

168 (52.8)

 
 

sp

88 (27.8)

89 (28.0)

 
 

unknown

35 (11.0)

32 (10.1)

 

EDSS, n (%)

0—4.0

104 (32.8)

110 (34.6)

chi-square p = 0.88

 

4.5—6.5

101 (31.9)

95 (29.9)

 
 

7.0—7.5

70 (22.1)

66 (20.8)

 
 

8.0—9.5

38 (12.0)

42 (13.2)

 
 

unknown

4 (1.3)

5 (1.6)

 
 

mean 100 mm VAS fatigue score (SD, min.—max.)

55.73 (24.4, 0—100)

52.11 (23.19, 0—100)

t-test p = 0.059

  1. pp = primary progressive, rr = relapsing remitting, sp = secondary progressive, VAS = visual analogue scale.