| Level of assessment | Level of appraisal |
---|---|---|
Experimental clinical trials conducted under ideal, but possibly artificial conditions | 1st step Explanatory trial describing possible causal effects of an action under ideal conditions, i.e., describing the efficacy | Not useful |
Descriptive studies conducted under day-to-day, real world conditions | 2nd step Pragmatic trial describing the effects of an action under real world conditions, i.e., describing the effectiveness | 3rd step Assessment of individual preferences under real world conditions, i.e. describing the value perceived by an individual |