Table 2 HRQoL of total study sample of children with SCD compared to healthy siblings and Dutch norm population of the KIDSCREEN-52
Children with SCD (n = 40) | Healthy siblings (n = 36) | SCD versus healthy siblings | Norm population (n = 1960) | SCD versus norm population | ||||
|---|---|---|---|---|---|---|---|---|
Mean | SD | Mean | SD | Effect size | Mean | SD | Point estimate of mean difference (95% CI) | |
Physical Well-being | 49 †* | 8.7 | 54 | 11.4 | 0.5 | 53 | 10.0 | -4 (-7; -1) |
Psychological Well-being | 53 | 9.3 | 55 | 9.6 | 0.2 | 53 | 8.8 | 0 (-3; +3) |
Moods & Emotions | 47 * | 8.9 | 47 * | 10.2 | 0 | 51 | 9.6 | -4 (-7; -1) |
Self-Perception | 52 | 8.8 | 53 | 10.8 | 0.1 | 52 | 10.1 | 0 (-3; +3) |
Autonomy | 48 * | 8.1 | 52 | 9.4 | 0.5 | 55 | 9.1 | -7 (-10; -4) |
Parent Relation | 50 * | 10.3 | 50 * | 10.4 | 0 | 53 | 9.1 | -3 (-6; 0) |
Financial Resources | 47 * | 10.0 | 46 * | 11.8 | 0.1 | 52 | 9.7 | -5 (-8; -2) |
Social Support & Peers | 50 | 11.3 | 51 | 12.4 | 0.1 | 52 | 9.3 | -2 (-5; 0) |
School Environment | 54 | 8.6 | 54 | 10.0 | 0 | 53 | 10.0 | 1 (-2; +4) |
Bullying | 45 | 11.5 | 47 | 11.5 | 0.6 | 49 | 10.4 | -4 (-7; -1) |