Figure 1

Proportions of children with SCD and healthy siblings with impaired HRQoL (≥1 SD below the mean of the Dutch norm population of the KIDSCREEN-52). The dotted line represents the 16% of children in the Dutch norm population of the KIDSCREEN-52 with impaired HRQoL. * 95% Confidence interval of the proportion of children with SCD or healthy siblings with impaired HRQoL exceeds the proportion in the Dutch norm population.