Skip to main content

Table 2 Health-related quality of life, psychological status, and limitations in activities of daily living of 337 COPD patients, according to ATS/ERS severity stages.

From: Factors affecting the relationship between psychological status and quality of life in COPD patients

   Total
n = 337
Mild
n = 19
Moderate
n = 161
Severe
n = 130
Very severe
n = 27
p*
Health-related quality of life        
SGRQ score (from 0 -no impairment- to 100)        
   Symptoms m (SD) 48.5 (17.6) 47.2 (13.8) 45.4 (16.5) 50.5 (18.4) 58.3 (18.7) 0.002
   Activity m (SD) 47.2 (24.5) 27.5 (21.5) 39.8 (21.3) 54.4 (23.6) 71.2 (21.4) < 0.001
   Impact m (SD) 26.5 (18.6) 13.4 (10.3) 22.0 (16.4) 30.5 (18.3) 43.2 (21.2) < 0.001
   Total m (SD) 36.5 (17.8) 23.5 (11.5) 31.4 (15.1) 41.0 (17.5) 54.2 (18.8) < 0.001
Activities of daily living (n = 333)        
Barthel Index (from 0 to 100) median (P25-P75) 100 (100-100) 100 (100-100) 100 (100-100) 100 (100-100) 100 (97.5-100) 0.013
Dependent (Barthel Index <100) n (%) 30 (9.0) 0 (0) 10 (6.2) 14 (10.9) 6 (24.0) 0.020
Psychological status        
HADS-anxiety score (from 0 to 21) median (P25-P75) 5 (2-8) 6 (1-11) 5 (3-8) 4 (2-7) 5 (3-8) 0.898
HADS-depression score (from 0 to 21) median (P25-P75) 3 (1-5.5) 2 (0-5) 3 (1-5) 3 (1-6) 4 (1-7) 0.533
HADS anxiety score ≥8 n (%) 91 (27.0) 8 (42.1) 46 (28.6) 29 (22.3) 8 (29.6) 0.267
HADS depression score ≥8 n (%) 46 (13.6) 4 (21.1) 20 (12.4) 16 (12.3) 6 (22.2) 0.349
HADS anxiety ≥8 and HADS depression ≥8 n (%) 30 (8.9) 4 (21.1) 13 (8.1) 9 (6.9) 4 (14.8) 0.122
HADS anxiety ≥8 and HADS depression <8 n (%) 61 (18.1) 4 (21.1) 33 (20.5) 20 (15.4) 4 (14.8) 0.664
HADS anxiety <8 and HADS depression ≥8 n (%) 16 (4.7) 0 (0) 7 (4.3) 7 (5.4) 2 (7.4) 0.732
  1. COPD, Chronic obstructive pulmonary disease; ERS/ATS, European Respiratory Society/American Thoracic Society; SGRQ, St. George's Respiratory Questionnaire; HADS, Hospital Anxiety and Depression Scale.
  2. * P-values in the table indicate that at least one of the severity groups differs from another severity group; Separate analysis for each severity group showed that significant differences were observed between consecutive stages from moderate to very severe, without differences in the mild group; Separate analysis for each severity group showed that significant differences were observed between all consecutive stages from mild to very severe.