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Table 5 Factors associated with agreement across all pairs of symptom observations (N = 21263)a

From: Health care providers underestimate symptom intensities of cancer patients: A multicenter European study

Factors possibly affecting agreement

Health care

provider

underestimation

Good

agreement

Health care

provider

overestimation

Chi-square

  

Number

%

Number

%

Number

%

 

Age

≤ 60

1013

10.9

8122

87.7

126

1.4

0.629

 

> 60

1268

10.7

10410

88.0

146

1.2

 

Body Mass Index

< 25

1378

10.3

11855

88.5

169

1.3

0.583

 

≥ 25

693

9.8

6274

88.9

89

1.3

 

KPS b

< 80

1808

11.1

14110

86.8

347

2.1

0.032

 

≥ 80

474

9.9

4240

88.2

94

2.0

 

Mini Mental State,

total score

≤ 23

265

9.5

2455

87.6

81

2.9

< 0.001

 

> 23

1927

11.3

14806

86.7

340

2.0

 

Time since

diagnosis (months)

≤ 3

550

12.5

3797

86.5

43

1.0

< 0.001

 

> 3

1420

9.6

13162

89.0

204

1.4

 

Gender

Female

1122

11.1

8812

87.5

136

1.4

0.261

 

Male

1161

10.5

9727

88.2

136

1.2

 

Department

Hospitalized patients

1992

12.1

14314

86.7

201

1.2

< 0.001

 

Out-patients

291

6.3

4225

92.1

71

1.5

 

Status of

opioid treatment

Recently initiated

593

15.4

3219

83.5

43

1.1

< 0.001

 

Stable dosing

1679

9.8

15159

88.6

228

1.3

 

Previous or ongoing

abuse alcohol

Yes

113

9.8

1017

88.5

19

1.7

0.304

 

No

2161

10.9

17477

87.9

252

1.3

 

Previous or ongoing

abuse drugs

Yes

19

9.2

180

87.4

7

3.4

0.024

 

No

2250

10.8

18283

87.9

267

1.3

 

Chemotherapy the

past 24 hours

Yes

331

10.4

2833

88.6

32

1.0

0.180

 

No

1952

10.9

15706

87.8

240

1.3

 

Profession of health

care provider c

Physician

859

10.6

6970

86.2

261

3.2

< 0.001

 

Nurse

1090

10.0

9573

88.1

208

1.9

 

Metastases

None

406

11.2

3176

87.7

39

1.1

0.430

 

One or more

1917

11.0

15352

87.7

233

1.3

 

Cancer diagnosis

Breast

292

10.0

2609

89.0

31

1.1

< 0.001

 

Female reproductive organs

183

11.5

1383

87.2

20

1.3

 
 

Gastrointestinal

455

9.4

4306

89.4

58

1.2

 
 

Haematological

142

11.5

1077

87.3

14

1.1

 
 

Head and neck

148

12.8

983

85.3

21

1.8

 
 

Lung

481

12.8

3241

86.0

46

1.2

 
 

Other

198

10.8

1607

87.6

29

1.6

 
 

Prostate

237

9.4

2233

89.0

40

1.6

 
 

Unknown origin

53

9.6

491

89.3

6

1.1

 
 

Urological

171

11.4

1317

87.5

18

1.2

 

Country

Denmark

3

0.9

304

95.3

11

3.5

< 0.001

 

Finland

25

7.7

295

90.8

5

1.5

 
 

Germany

662

22.4

2231

75.5

61

2.1

 
 

Greece

5

9.3

48

88.9

1

1.9

 
 

Iceland

105

6.6

1437

90.3

49

3.1

 
 

Italy

137

3.1

4196

96.1

34

0.8

 
 

Lithuania

44

7.5

533

90.5

12

2.0

 
 

Norway

546

10.5

4578

88.4

54

1.0

 
 

Sweden

182

14.0

1107

85.3

9

0.7

 
 

Switzerland

281

22.8

937

76.1

13

1.1

 
 

United Kingdom

293

9.2

2874

89.8

33

1.0

 
  1. aNumber of paired symptom observations. Across one pair of raters and 11 questions for 1933 patients (1 × 11 × 1933 = 21263) (varies due to missing data).
  2. bKarnofsky performance status
  3. cFor 204 patients, the profession of the health care provider was not reported.