From: Detecting exacerbations using the Clinical COPD Questionnaire
Δ CCQ total score in unrecovered exacerbations | ||||
---|---|---|---|---|
Cut off 0.1 points | Cut off 0.2 points | Cut off 0.3 points | Cut off 0.4 points | |
Sensitivity, % | 72.9 (60.5 - 82.8) | 62.5 (50.3 - 73.4) | 47.9 (36.4 - 58.9) | 39.6 (29.2 - 49.1) |
Specificity, % | 69.1 (66.1 - 71.3) | 82.0 (79.3 - 84.4) | 87.6 (85.0 - 90.0) | 93.1 (90.8 - 95.2) |
PPV, % | 34.3 (28.5 - 39.0) | 43.5 (35.0 - 51.0) | 46.0 (35.0 - 56.6) | 55.9 (41.3 - 69.3) |
NPV, % | 92.0 (88.4 - 94.9) | 90.8 (87.8 - 93.5) | 88.4 (85.8 - 90.8) | 87.4 (85.3 - 89.4) |
Overall accuracy, % | 69.8 (65.3 - 73.4) | 78.5 (74.1 - 82.4) | 80.4 (76.2 - 84.4) | 83.4 (79.6 - 86.8) |
True positive, n | 35 | 30 | 23 | 19 |
False positive, n | 67 | 39 | 27 | 15 |
Unreported, n (% of TP) | 26 (74) | 22 (73) | 16 (70) | 13 (68) |
Exacerbation type I, n (% unreported) | 8 (31) | 5 (23) | 4 (25) | 4 (31) |
Exacerbation type 2, n (% unreported) | 11 (42) | 10 (45) | 6 (37.5) | 5 (38) |
Exacerbation type 3, n (% unreported) | 7 (27) | 7 (32) | 6 (37.5) | 4 (31) |