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Table 3 Discriminative properties of four ΔCCQ total score cut off points for unrecovered exacerbations

From: Detecting exacerbations using the Clinical COPD Questionnaire

 

Δ CCQ total score in unrecovered exacerbations

 

Cut off

0.1 points

Cut off

0.2 points

Cut off

0.3 points

Cut off

0.4 points

Sensitivity, %

72.9

(60.5 - 82.8)

62.5

(50.3 - 73.4)

47.9

(36.4 - 58.9)

39.6

(29.2 - 49.1)

Specificity, %

69.1

(66.1 - 71.3)

82.0

(79.3 - 84.4)

87.6

(85.0 - 90.0)

93.1

(90.8 - 95.2)

PPV, %

34.3

(28.5 - 39.0)

43.5

(35.0 - 51.0)

46.0

(35.0 - 56.6)

55.9

(41.3 - 69.3)

NPV, %

92.0

(88.4 - 94.9)

90.8

(87.8 - 93.5)

88.4

(85.8 - 90.8)

87.4

(85.3 - 89.4)

Overall accuracy, %

69.8

(65.3 - 73.4)

78.5

(74.1 - 82.4)

80.4

(76.2 - 84.4)

83.4

(79.6 - 86.8)

True positive, n

35

30

23

19

False positive, n

67

39

27

15

Unreported,

n (% of TP)

26 (74)

22 (73)

16 (70)

13 (68)

Exacerbation type I,

n (% unreported)

8 (31)

5 (23)

4 (25)

4 (31)

Exacerbation type 2,

n (% unreported)

11 (42)

10 (45)

6 (37.5)

5 (38)

Exacerbation type 3,

n (% unreported)

7 (27)

7 (32)

6 (37.5)

4 (31)

  1. Overall accuracy = (number of true-positives+ true negatives)/(number of true positives + true negatives + false positives + false negatives). PPV: Positive Predicted Value. NPV: Negative Predicted Value. TP: True Positive. Data are presented as value or ratio (95% confidence interval).