Relationship between the EQ-5D index and measures of clinical outcomes in selected studies of cardiovascular interventions

Table 3 Relationship between variables and the EQ-5D index - pooled effect and heterogeneity from evidence synthesis across studies

Variable	Pooled effect (95% CI)	Heterogeneity as measured by I², p-value
Age (10 year increment)	0.02 (-0.01, 0.04)	61%, < 0.001
Sex (Men vs. women)	0.09 (0.04, 0.14)	93%, <0.001
ETT (1 minute increment)	0.019 (0.014, 0.025)	36%, 0.10
CCS (1 class increase)	0.11 (0.09, 0.13)	86%, <0.001
SAQ - ECS (10 unit increment)	0.066 (0.053, 0.079)	87%, <0.001
SAQ - ASS (10 unit increment)	0.039 (0.029, 0.049)	51%, 0.02
SAQ - AFS (10 unit increment)	0.052 (0.039, 0.067)	87%, <0.001
SAQ - TSS (10 unit increment)	0.044 (0.032, 0.056)	0, 0.45
SAQ - DPS (10 unit increment)	0.063 (0.047, 0.079)	87%, <0.001
SF-6D (0.10 unit increment)	0.17 (0.16, 0.19)	83%, <0.001

Key: EQ-5D - EuroQol 5D, I² - I² index for quantifying heterogeneity, ETT - Treadmill exercise test, CCS - Canadian Cardiovascular Society angina classification, SAQ - Seattle Angina Questionnaire, ECS - exertional capacity scale, ASS - angina severity scale, AFS - anginal frequency scale, TSS - treatment satisfaction scale, DPS - disease perception scale, SF-6D - short form 6D

ISSN: 1477-7525