Table 1 Summary of studies used and disease/treatment group and treatment variables used in regression models
Name | Short form | Inclusion/Exclusion Criteria | Study type | Study size | Cardiac subgroup | Disease/ treatment groups (random effect) | Treatment |
|---|---|---|---|---|---|---|---|
Cost-effectiveness of functional cardiac testing in the diagnosis and management of CHD [12] | CECaT | I: established or suspected CHD referred for angiography E: recent MI, revascularization, urgent need for revascularization, contraindications to study tests | Diagnosis/ management (RCT) | 898 | Coronary disease diagnosis | CECaT baseline CECaT MM CECaT PCI CECaT CABG | Pre-treatment MM PCI CABG |
Appropriateness for coronary revascularization [1] | ACRE | I: Consecutive patients having coronary angiography E: None | Diagnosis/ management (cohort) | 2419 | Coronary revascularization | ACRE MM ACRE PCI ACRE CABG | MM PCI CABG |
Implantable Cardioverter Defibrillator (ICD) therapy in different patient groups [28] | ICD | I: patients implanted with an ICD at Papworth or Liverpool hospitals between 1991 and 1999 and a random sample of those implanted in 2000 and 2001 | Diagnosis/ management (cohort) | 229 | Cardiac arrythmias | ICD | ICD |
Percutaneous myocardial revascularization (PMR) compared to continued medical therapy [29] | PMR | I: angina refractory to medication or revascularization E: implanted devices, significant comorbidity, contraindications to study treatments | Angina (RCT) | 73 | Angina | PMR | Pre-treatment* MM PMR |
Transmyocardial laser revascularization (TMR) compared to continued medical therapy [30] | TMR | I: angina refractory to medication or revascularization E: implanted devices, significant comorbidity, contraindications to study treatments | Angina (RCT) | 188 | Angina | TMR baseline TMR MM TMR | Pre-treatment* MM TMR |
Spinal cord stimulation (SCS) compared to PMR [31] | SPiRiT | I: angina refractory to medication or revascularization E: implanted devices, significant comorbidity, contraindications to study treatments | Angina (RCT) | 68 | Angina | SPiRiT baseline PMR SCS | Pre-treatment* PMR SCS |
Evaluation of ventricular assist devices (VAD) patients compared to patients on transplant waiting list (Tx WL) [3] | Tx WL | I: a sample of patients listed for transplant between April 2002 and December 2004 | Heart failure (cohort) | 47 | Heart failure | Tx WL | Pre-treatment* |
| Â | VAD | I: all patients with VADs implanted as part of NSCAG funded program between April 2002 and December 2004 | Heart failure (cohort) | 35 | Heart failure | VAD Post-tx (post-transplant) | VAD Tx |