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Table 2 Clinical characteristics and co-morbid chronic illness of study sample

From: Health-related quality of life of Southern Chinese with chronic hepatitis B infection

  Uncomplicated CHB (n = 156) Impaired LF (n = 102) Cirrhosis (n = 139) HCC (n = 123) Overall (n = 520)
Ever taken anti-viral treatment (%)†      
   No 65.4 62.7 34.5 67.5 57.1
   Yes 34.6 37.3 65.5 32.5 42.9
Liver function (%)†      
   Normal LF 100.0 0.0 0.0 18.7 34.4
   Impaired LF without cirrhosis 0.0 100.0 0.0 1.6 20.0
   Cirrhosis      
Child-Pugh A NA NA 64.0 68.3 33.3
Child-Pugh B NA NA 17.3 8.1 6.5
Child-Pugh C NA NA 18.7 3.3 5.8
Duration of illness (mean, SD) 12.8 ± 8.1 12.3 ± 8.7 11.6 ± 8.5 13.6 ± 10.6 12.6 ± 9.0
Biomarkers      
   ALT, U/L (mean, SD)† 27.4 ± 8.7 150.7 ± 306.5 48.2 ± 52.6 55.1 ± 47.3 67.8 ± 154.1
   AST, U/L (mean, SD)† 24.1 ± 7.3 130.8 ± 272.0 48.2 ± 26.6 52.1 ± 38.8 57.4 ± 108.9
   Abnormal AFP, ng/ml (%)*† 0.0 14.0 10.5 29.4 14.2
   Bilirubin, umol/L (mean, SD)† 14.3 ± 7.0 20.1 ± 23.3 38.1 ± 56.5 18.4 ± 15.0 23.9 ± 35.3
Co-morbidity (%)      
   Hypertension 23.7 17.6 19.4 26.0 21.9
   Diabetes mellitus† 6.4 3.9 19.4 17.9 12.1
   Heart disease 3.8 3.9 6.5 5.7 5.0
   Stroke 0.0 1.0 1.4 0.8 0.8
   Pulmonary disease 6.4 2.0 5.0 3.3 4.4
   Joint disease 3.2 3.9 3.6 3.3 3.5
   Psychological disease 4.5 4.9 3.6 8.9 5.4
   Others 12.8 10.8 11.5 19.5 13.7
   Any chronic illness† 38.5 31.4 51.8 53.7 44.2
  1. LF = Liver Function; HCC = Hepatocellular Carcinoma; ALT, Alanine Aminotransferase; AST, Aspartate Aminotransferase; AFP, Alpha-fetoprotein.
  2. Notes:
  3. *Abnormal AFP refers to AFP value above 20 ng/ml.
  4. † Significant difference among the four CHB groups (p < 0.05).