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Table 2 Clinical characteristics and co-morbid chronic illness of study sample

From: Health-related quality of life of Southern Chinese with chronic hepatitis B infection

 

Uncomplicated CHB (n = 156)

Impaired LF (n = 102)

Cirrhosis (n = 139)

HCC (n = 123)

Overall (n = 520)

Ever taken anti-viral treatment (%)†

     

   No

65.4

62.7

34.5

67.5

57.1

   Yes

34.6

37.3

65.5

32.5

42.9

Liver function (%)†

     

   Normal LF

100.0

0.0

0.0

18.7

34.4

   Impaired LF without cirrhosis

0.0

100.0

0.0

1.6

20.0

   Cirrhosis

     

Child-Pugh A

NA

NA

64.0

68.3

33.3

Child-Pugh B

NA

NA

17.3

8.1

6.5

Child-Pugh C

NA

NA

18.7

3.3

5.8

Duration of illness (mean, SD)

12.8 ± 8.1

12.3 ± 8.7

11.6 ± 8.5

13.6 ± 10.6

12.6 ± 9.0

Biomarkers

     

   ALT, U/L (mean, SD)†

27.4 ± 8.7

150.7 ± 306.5

48.2 ± 52.6

55.1 ± 47.3

67.8 ± 154.1

   AST, U/L (mean, SD)†

24.1 ± 7.3

130.8 ± 272.0

48.2 ± 26.6

52.1 ± 38.8

57.4 ± 108.9

   Abnormal AFP, ng/ml (%)*†

0.0

14.0

10.5

29.4

14.2

   Bilirubin, umol/L (mean, SD)†

14.3 ± 7.0

20.1 ± 23.3

38.1 ± 56.5

18.4 ± 15.0

23.9 ± 35.3

Co-morbidity (%)

     

   Hypertension

23.7

17.6

19.4

26.0

21.9

   Diabetes mellitus†

6.4

3.9

19.4

17.9

12.1

   Heart disease

3.8

3.9

6.5

5.7

5.0

   Stroke

0.0

1.0

1.4

0.8

0.8

   Pulmonary disease

6.4

2.0

5.0

3.3

4.4

   Joint disease

3.2

3.9

3.6

3.3

3.5

   Psychological disease

4.5

4.9

3.6

8.9

5.4

   Others

12.8

10.8

11.5

19.5

13.7

   Any chronic illness†

38.5

31.4

51.8

53.7

44.2

  1. LF = Liver Function; HCC = Hepatocellular Carcinoma; ALT, Alanine Aminotransferase; AST, Aspartate Aminotransferase; AFP, Alpha-fetoprotein.
  2. Notes:
  3. *Abnormal AFP refers to AFP value above 20 ng/ml.
  4. † Significant difference among the four CHB groups (p < 0.05).