Table 1 Patient profile: Demographics and clinical features
Demographics and Clinical Characteristics | PhysR-PSS | Controls |
|---|---|---|
N = 277 | N = 606 | |
Age (Mean ± S.D.) | 62 ± 12.6 | 61 ± 12.2 |
Gender (% Female) | 90% | 92% |
Employment Status | ||
Employed (net) | 38% | 49% (1,2) |
Not Employed (due to disability) | 12%* | 0% |
Disease Duration (Mean ± S.D.) | 9.0 ± 8.4 | N/A |
Time from first symptom to diagnosis (Mean ± S.D.) | 7.1 ± 9.4 | N/A |
Extra-glandular Symptoms | ||
Raynaud's | 51%* | 14% |
Forgetfulness | 67% | 62% |
Depression (reported by patient) | 54%* | 41% |
Lymph node pain or swelling | 41%* | 12% |
Muscle pain | 60%* | 42% |
Joint pain | 78%* | 52% |
Neuropathy ("pins and needles," tingling and/or numbness in extremities) | 70%* | 41% |
Extra-glandular Conditions | ||
Purpura/petechia | 14%* | 4% |
Vasculitis | 17%* | 2% |
CNS Sjögren's | 22%* | 1% |
Leucopenia | 21%* | 5% |
Lymphoma | 12%* | 2% |
Lung Disease | 16%* | 6% |
Ocular Sicca-related Disorders | ||
Chronic blepharitis | 30%* | 5% |
Corneal scarring | 18%* | 2% |