Skip to main content

Table 4 Comparison of Parent Health-related Quality of Life and Family Functioning in Children With Sickle Cell Disease and Urban Controls

From: A psychometric evaluation of the PedsQL™ Family Impact Module in parents of children with sickle cell disease

  Controls a Mild SCD b Severe SCD c  
Scale N Median (IQR) N Median (IQR)
Effect Size
N Median (IQR)
Effect Size
Differences*
Summary Scores        
   Total Score 73 75.7 (62.5, 91.3) 44 78.8 (67.4, 91.3) 51 73.6 (57.4, 83.6)  
   -   0.109   -0.211  
   Parent HRQL 72 74.4 (59.4, 90.0) 44 78.8 (65.4, 93.1) 53 73.5 (60.0, 84.7)  
   -   0.168   -0.051  
   Family Functioning 68 81.3 (61.8, 100.0) 44 76.6 (68.8, 98.4) 50 75.0 (56.3, 93.8)  
     0.038   -0.165  
Dimensions        
   Physical Functioning 72 70.8 (54.2, 91.7) 43 66.7 (50.0, 91.7) 52 68.8 (50.0, 77.1)  
     -0.100   -0.173  
   Emotional Functioning 73 75.0 (60.0, 100.0) 44 80.0 (70.0, 100.0) 53 70.0 (60.0, 90.0)  
     0.185   -0.111  
   Social Functioning 72 81.3 (59.4, 100.0) 44 93.8 (68.8, 100.0) 52 87.5 (59.4, 100.0)  
     0.186   0.085  
   Cognitive Functioning 72 75.0 (52.5, 97.5) 44 92.5 (60.0, 100.0) 52 75.0 (55.0, 90.8)  
     0.335   0.066  
   Communication 73 91.7 (75.0, 100.0) 44 95.8 (66.7, 100.0) 50 66.7 (58.3, 100.0) a, b > c
     -0.024   -0.403  
   Worry 72 80.0 (50.0, 100.0) 44 77.5 (50.0, 100.0) 50 55.0 (40.0, 80.0) a, b > c
     0.003   -0.532  
   Daily Activities 70 75.0 (50.0, 100.0) 44 75.0 (58.3, 100.0) 49 66.7 (50.0, 91.7)  
     -0.001   -0.225  
   Family Relationships 68 87.5 (65.0, 100.0) 44 85.0 (62.5, 100.0) 50 80.0 (60.0, 100.0)  
     0.071   -0.088  
  1. * Differences based on Kruskal-Wallis Tests followed by pair-wise Wilcoxon tests if global null hypothesis was rejected