Table 4 Comparison of Parent Health-related Quality of Life and Family Functioning in Children With Sickle Cell Disease and Urban Controls

Scale

N

Median (IQR)

N

Median (IQR)

Effect Size^†

N

Median (IQR)

Effect Size^†

Differences*

Summary Scores

   Total Score

73

75.7 (62.5, 91.3)

44

78.8 (67.4, 91.3)

51

73.6 (57.4, 83.6)

-

0.109

-0.211

   Parent HRQL

72

74.4 (59.4, 90.0)

44

78.8 (65.4, 93.1)

53

73.5 (60.0, 84.7)

-

0.168

-0.051

   Family Functioning

68

81.3 (61.8, 100.0)

44

76.6 (68.8, 98.4)

50

75.0 (56.3, 93.8)

0.038

-0.165

Dimensions

   Physical Functioning

72

70.8 (54.2, 91.7)

43

66.7 (50.0, 91.7)

52

68.8 (50.0, 77.1)

-0.100

-0.173

   Emotional Functioning

73

75.0 (60.0, 100.0)

44

80.0 (70.0, 100.0)

53

70.0 (60.0, 90.0)

0.185

-0.111

   Social Functioning

72

81.3 (59.4, 100.0)

44

93.8 (68.8, 100.0)

52

87.5 (59.4, 100.0)

0.186

0.085

   Cognitive Functioning

72

75.0 (52.5, 97.5)

44

92.5 (60.0, 100.0)

52

75.0 (55.0, 90.8)

0.335

0.066

   Communication

73

91.7 (75.0, 100.0)

44

95.8 (66.7, 100.0)

50

66.7 (58.3, 100.0)

a, b > c

-0.024

-0.403

   Worry

72

80.0 (50.0, 100.0)

44

77.5 (50.0, 100.0)

50

55.0 (40.0, 80.0)

a, b > c

0.003

-0.532

   Daily Activities

70

75.0 (50.0, 100.0)

44

75.0 (58.3, 100.0)

49

66.7 (50.0, 91.7)

-0.001

-0.225

   Family Relationships

68

87.5 (65.0, 100.0)

44

85.0 (62.5, 100.0)

50

80.0 (60.0, 100.0)

0.071

-0.088