Table 3 Effects of weight loss on QOL and clinical outcomes (ancillary analyses)
Variables | Baseline | 3 mos | 6 mos | 12 mos | Group effect P* |
|---|---|---|---|---|---|
Primary QoL outcome | Â | Â | Â | Â | Â |
FACT-G | Â | Â | Â | Â | 0.26 |
   WL | 81.4 (14.0) | 83.5 (15.7) | 84.8 (14.7) | 82.3 (15.4) |  |
   WG | 78.9 (11.7) | 78.1 (13.3) | 79.8 (12.6) | 80.1 (13.8) |  |
Secondary QoL outcomes | Â | Â | Â | Â | Â |
Physical well-being (0–28) |  |  |  |  | 0.79 |
   WL | 24.7 (3.3) | 24.5 (4.6) | 24.7 (4.7) | 24.2 (4.8) |  |
   WG | 23.1 (3.0) | 22.5 (4.0) | 23.5 (3.7) | 22.8 (3.5) |  |
Functional well-being (0–28) |  |  |  |  |  |
   WL | 21.9 (5.6) | 22.8 (5.3) | 23.3 (5.0) | 21.9 (6.1) | 0.65 |
   WG | 20.5 (5.2) | 21.2 (5.8) | 20.8 (5.4) | 21.2 (6.2) |  |
Emotional well-being (0–24) |  |  |  |  |  |
   WL | 18.2 (4.3) | 20.0 (4.1) | 20.0 (4.3) | 19.5 (4.2) | 0.02 |
   WG | 18.9 (4.0) | 18.4 (4.2) | 18.9 (4.2) | 19.3 (4.1) |  |
Social/family well-being (0–28) |  |  |  |  |  |
   WL | 16.6 (3.2) | 16.2 (3.4) | 17.0 (2.8) | 16.7 (2.8) | 0.98 |
   WG | 16.4 (3.0) | 16.0 (3.0) | 16.5 (2.9) | 16.8 (3.2) |  |
Fatigue (0–52) |  |  |  |  |  |
   WL | 39.0 (10.2) | 41.6 (10.5) | 41.4 (12.1) | 42.0 (10.5) | 0.07 |
   WG | 36.9 (9.3) | 36.3 (10.5) | 37.3 (10.7) | 36.9 (9.5) |  |
Endometrial subscale (0–64) |  |  |  |  |  |
   WL | 54.3 (6.6) | 54.3 (7.7) | 55.2 (8.1) | 55.5 (6.9) | 0.55 |
   WG | 52.8 (5.1) | 52.7 (6.2) | 53.1 (5.7) | 53.3 (5.9) |  |
WEL | Â | Â | Â | Â | Â |
Negative emotions (0–36) |  |  |  |  | < 0.01 |
   WL | 16.7 (10.9) | 24.3 (10.5) | 25.6 (9.3) | 25.6 (9.7) |  |
   WG | 20.0 (10.3) | 22.4 (9.5) | 20.5 (3.3) | 20.6 (9.8) |  |
Food Availability (0–36) |  |  |  |  | 0.03 |
   WL | 16.5 (10.4) | 24.0 (9.6) | 23.8 (9.9) | 24.4 (10.4) |  |
   WG | 19.5 (8.3) | 22.8 (9.0) | 20.7 (9.4) | 21.4 (9.4) |  |
Social pressure (0–36) |  |  |  |  | 0.20 |
   WL | 25.2 (9.2) | 28.4 (7.5) | 28.1 (7.5) | 29.1 (7.2) |  |
   WG | 22.7 (8.1) | 26.1 (8.0) | 23.9 (8.2) | 25.2 (7.6) |  |
Positive activities (0–36) |  |  |  |  | 0.10 |
   WL | 23.0 (7.9) | 27.5 (6.2) | 27.5 (5.3) | 27.8 (5.0) |  |
   WG | 25.1 (6.5) | 27.5 (6.9) | 25.4 (7.0) | 27.4 (4.6) |  |
Physical discomfort (0–36) |  |  |  |  |  |
   WL | 25.5 (9.2) | 29.6 (7.0) | 30.0 (6.9) | 30.8 (7.1) | 0.01 |
   WG | 27.0 (7.4) | 28.1 (6.5) | 26.9 (6.2) | 28.0 (5.7) |  |
Total (0–180) |  |  |  |  | <0.01 |
   WL | 106.9 (37.4) | 133.8 (36.0) | 135.0 (33.8) | 137.6 (33.9) |  |
   WG | 114.3 (35.5) | 126.9 (33.9) | 117.4 (34.4) | 122.6 (31.4) |  |
Beck depression inventory | Â | Â | Â | Â | Â |
   WL | 9.3 (7.0) | - | - | 7.0 (6.5) | 0.03 |
   WG | 10.9 (8.8) | - | - | 9.7 (7.9) | 0.14 |
TFEQ | Â | Â | Â | Â | Â |
Restraint (0–21) |  |  |  |  |  |
   WL | 10.1 (4.5) | - | - | 12.9 (4.2) | <0.01 |
   WG | 10.2 (5.4) | - | - | 10.3 (5.3) | 0.74 |
Disinhibition (0–16) |  |  |  |  |  |
   WL | 7.8 (3.0) | - | - | 6.9 (3.3) | 0.05 |
   WG | 8.1 (4.1) | - | - | 8.4 (4.1) | 0.48 |
Hunger (0–14) |  |  |  |  |  |
   WL | 6.1 (3.8) | - | - | 5.1 (2.5) | 0.21 |
   WG | 5.3 (3.1) | - | - | 5.1 (3.1) | 0.51 |