Author(s) | Year | Sample | HRQOL measure(s) | Results* |
---|---|---|---|---|
Andrykowski et al. [92] | 1994 | 42 leukemia | Depressed mood + Functional QOL + MAC | Anxious preoccupation and functional QOL were independent predictors of survival. |
Tannock et al. [93] | 1996 | 161 symptomatic hormone-resistant prostate | EORTC QLQ-C30 + QLQ-PR25 + PROSQOLI | Appetite loss, pain, and physical functioning were associated with survival. |
Wisloff and Hjorth [94] | 1997 | 468 multiple myeloma | EORTC QLQ-C30 | Physical functioning was independent prognostic factor of survival. |
Meyers et al. [95] | 2000 | 80 brain (recurrent glioblastoma multiforme or anaplastic astrocytoma) | FACT-Br + ADL | Measures of QOL and ADL were not independently related to survival. |
Jerkeman et al. [96] | 2001 | 95 aggressive lymphoma | EORTC QLQ-C30 | Pretreatment global QOL was an independent prognostic marker of overall survival. |
Roychowdury et al. [97] | 2003 | 364 locally advanced and metastatic bladder | EORTC QLQ-C30 | Longer survival was associated with high physical functioning, low role functioning and no anorexia. |
Sehlen et al. [98] | 2003 | 153 brain tumors | FACT-G | The FACT-G sum score was a significant predictor of survival. |
Collette et al. [99] | 2004 | 391 symptomatic metastatic hormone-resistant prostate cancer | EORTC QLQ-C30 | Insomnia and appetite loss were significant independent predictors of survival. |
Monk et al. [100] | 2005 | 179 advanced cancer of cervix | FACT-G + Cervix subscale + FACT/GOG-Ntx+ BPI | Baseline FACT-Cx (FACT-G + Cervix subscale) scores was associated with survival. |
Brown et al. [101] | 2005 | 273 brain (high grade gloima) | LASA scales (to measure overall QOL)+ FACT-Br + Fatigue (SDS) + Sleep (ESS) + depression (POMS-SF)+ Mental health (MMSE) | Changes in QOL measures over time were not found to be associated with survival. |
Brown et al. [102] | 2006 | 194 brain (high grade glioma) | LASA scales (to measure overall QOL)+ FACT-Br + Fatigue (SDS) + Sleep (ESS) + depression (POMS-SF) + Mental health (MMSE) | Fatigue was significant independent predictor of survival. |
Yeo et al. [103] | 2006 | 233 unresectable hepatocellular | EORTC QLQ-C30 | Appetite loss, physical and role functioning scores were significant predictor of survival. |
Lis et al. [104] | 2006 | 55 pancreatic cancer | Ferrans and Powers QLI | Health and physical subscale was marginally significant predictor of survival. |
Dubois et al. [105] | 2006 | 202 refractory multiple myeloma | EORTC QLQ-C30 + QLQ-MY24 + FACIT-F + FACT/GOG-Ntx | Fatigue was significant predictor of survival. |
Sullivan et al. [106] | 2006 | 809 metastatic hormon-refractory prostate | EORTC QLQ-C30 + FACT-P | Baseline QOL scores (global QOL, physical, role, and social functioning and pain, fatigue and appetite loss) were significant predictors of survival. |
Mauer et al. [107] | 2007 | 247 brain (anaplastic oligodenroglimas) | EORTC QLQ-C30 + EORTC QLQ-BN20 | Emotional functioning, communication deficit, future uncertainty, and weakness of legs were significant prognostic of survival. Baseline QOL scores added little to clinical factors to predict survival. |
Mauer et al. [108] | 2007 | 490 brain (new diagnosed glioblastoma) | EORTC QLQ-C30 + QLQ-BN20 | Cognitive functioning, global health status, and social functioning were significant prognostic factors of survival. Baseline QOL scores added little to clinical factors to predict survival. |
Fielding and Wong [44] | 2007 | 358 liver and lung | FACT-G | Global QOL scores did not predict survival in liver and lung cancer. Physical well-being and appetite predicted survival in lung cancer. |
Viala et al. [109] | 2007 | 202 multiple myeloma | EORTC QLQ-C30, EORTC QLQ-MY24, FACIT-F, FACT/GOG-Ntx | 14 out of 21 patient-reported outcomes were significant predictors of mortality. Clinical plus PRO data increased the predictive power. |
Bonnetain et al. [110] | 2008 | 538 advanced hepatocellular carcinoma | Spitzer QLI | Baseline QOL was independent prognostic factor for survival. |
Carey et al. [111] | 2008 | 244 advanced ovarian cancer | EORTC QLQ-C30 | Performance status and global QOL scores at baseline were prognostic factors for both progression-free survival and overall survival. |
Gupta et al. [112] | 2008 | 90 ovarian cancer | Ferrans and Powers QLI | No statistically significant prognostic association of patient satisfaction with QOL was observed with survival. |
Robinson et al. [113] | 2008 | 86 pancreatic cancer | FACIT-F+ FAACT + BPI + SF-36 | Fatigue strongly predicted survival. |
Strasser-Weippl and Ludwig [114] | 2008 | 92 multiple myeloma | EORTC QLQ-C30 | Role, emotional, cognitive and social functioning but not physical functioning and global QOL were found to be independent prognostic factors of overall survival. |