Table 6 Studies on relationship between quality of life data and survival in patients with head and neck cancer
Author(s) | Year | Sample | HRQOL measure(s) | Results* |
|---|---|---|---|---|
De Boer [77] | 1998 | 133 head and neck | Self-reported psychosocial and physical functioning | Patients with higher perceived physical abilities were likely to survive more and less likely to develop a recurrence. |
de Graeff et al. [78] | 2001 | 208 head and neck | EORTC QLQ-C30 + QLQ-H&N35 + CES-D | Cognitive functioning was predictor of survival while physical functioning; mood and global QOL were not. |
Fang et al. [79] | 2004 | 102 advanced head and neck | EORTC QLQ-C30 + EORTC QLQ-H&N35 | Baseline fatigue was predictive of survival while changes in QOL scores during treatment was not. |
Mehanna and Morton [80] | 2006 | 200 head and neck | AQLQ + LSS + GHQ | QOL at diagnosis was not significant predictor of survival. One year after diagnosis poor life satisfaction score and pain were significant predictors of survival. |
Nordgren et al. [81] | 2006 | 89 head and neck | EORTC QLQ-C30 | Physical functioning was significant predictor of survival. |
Coyne et al. [82] | 2007 | 1093 locally advanced head and neck cancer | Emotional well-being (FACT-G) | Emotional functioning was not an independent predictor of survival. |
Siddiqui et al. [83] | 2008 | 1093 locally advanced head and neck cancer | FACT-H&N | The FACT-H&N score was independently predictive of loco-regional control but not overall survival. |
Karvonen-Gutierrez et al. [84] | 2008 | 495 head and neck cancer | SF-36, HNQOL | The SF-36 physical component summary score and three domains of the HNQOL (pain, eating and speech) were associated with survival. |