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Table 1 Baseline characteristics for all eligible patients in the REVEAL study

From: Adalimumab improves health-related quality of life in patients with moderate to severe plaque psoriasis compared with the United States general population norms: Results from a randomized, controlled Phase III study

 

Treatment Group

 
 

Adalimumab (N = 808)

Placebo (N = 397)

P-value 1

Age (yrs), mean ± SD1

44.1 ± 13.2

45.4 ± 13.4

0.1177

Sex, n (% female)1

266 (32.9)

141 (35.5)

0.3996

Race, n (%)2

  

0.5432

   White

738 (91.3)

358 (90.2)

 

   Black

27 (3.3)

20 (5.0)

 

   Asian

21 (2.6)

7 (1.8)

 

   American Indian/Alaska Native

3 (0.4)

1 (0.3)

 

   Other

19 (2.4)

11 (2.8)

 

Ethnicity, n (%)2

  

0.3434

   Not Hispanic or Latino

754 (93.3)

364 (91.7)

 

   Hispanic or Latino

54 (6.7)

33 (8.3)

 

Psoriasis history

   

   Duration of psoriasis (yrs), mean ± SD1

18.6 ± 12.0

18.8 ± 12.0

0.7309

   Concomitant psoriatic arthritis, (% yes)2

222 (27.5)

113 (28.5)

0.7326

   Prior systemic psoriasis therapy, (% yes)2

260 (32.2)

128 (32.2)

1.0000

Psoriasis baseline assessments

   

   Percentage of body surface area affected by psoriasis, mean ± SD2

25.8 ± 15.5

25.6 ± 14.8

0.8796

   Psoriasis Area and Severity Index, mean ± SD2

19.0 ± 7.1

18.8 ± 7.1

0.7787

Physician's global assessment score, n (% yes) 2

  

1.0000

   Moderate2

416 (51.5)

219 (55.2)

 

   Severe

341 (42.2)

155 (39.0)

 

   Very severe

51 (6.3)

23 (5.8)

 
  1. 1t-Test.
  2. 2Fisher exact test or chi-square test.
  3. 3P-value for comparison between adalimumab versus placebo.