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Table 2 Change in the RDQ scales from baseline to 2 weeks, by patient rating of the Overall Treatment Evaluation (OTE)

From: The Reflux Disease Questionnaire: a measure for assessment of treatment response in clinical trials

OTE N Heartburn Regurgitation Dyspepsia GERDa
   Mean SD Mean SD Mean SD Mean SD
Esomeprazole
Worse 6 0.04 2.00 -0.42 0.41 -0.08 1.47 -0.19 1.20
The same 36 0.76 1.48 0.68 1.11 0.31 1.24 0.71 0.99
A little better 43 1.60 1.46 1.52 1.08 1.27 1.64 1.56 0.97
Much better 231 2.74 1.26 2.25 1.42 1.94 1.59 2.51 1.08
All 316 2.31 1.52 1.92 1.47 1.64 1.66 2.12 1.26
Placebo
Worse 3 0.42 1.18 -0.25 0.25 0.50 0.43 0.08 0.63
The same 26 0.42 1.54 0.37 1.30 0.27 1.41 0.37 1.08
A little better 28 0.88 1.0 1.05 1.10 0.78 1.20 0.90 0.72
Much better 22 2.10 1.26 1.38 1.82 1.65 1.68 1.74 1.33
All 79 1.05 1.43 0.86 1.43 0.86 1.50 0.93 1.17
  1. aHeartburn and regurgitation subscales combined. SD, standard deviation.