Impact of schizophrenia and schizophrenia treatment-related adverse events on quality of life: direct utility elicitation

Table 4 Determinants of utility values

Explanatory variable	Coefficient (standard error) – Unrestricted regression	Coefficient (standard error) – Parsimonious regression
Constant	0.794 (0.062)*	0.856 (0.021)*
Weight gain	- 0.090 (0.021)*	- 0.089 (0.015)*
Diabetes	- 0.151 (0.021)*	- 0.151 (0.019)*
Hyperprolactinemia	- 0.087 (0.021)*	- 0.089 (0.014)*
Relapse	- 0.355 (0.021)*	- 0.358 (0.025)*
EPS	- 0.256 (0.021)*	- 0.256 (0.022)*
Patients	0.071 (0.034)*	0.077 (0.033)*
Age	0.002 (0.001)	na
Female	- 0.039 (0.033)	na

Diagnostic parameters (unrestricted regression):
Number of observations = 738.
R² (within) = 0.3871; R² (between) = 0.0726; R² (overall) = 0.2339.
Wald chi²(8) = 394.56.
Prob > chi² < 0.0001.
Joint significance test on "Age" and "Female": chi²(2) = 3.81; Prob > chi² = 0.1492
Diagnostic parameters (parsimonious regression):
Number of observations = 738.
R² (within) = 0.3891; R² (between) = 0.0424; R² (overall) = 0.2215.
Wald chi²(6) = 397.18.
Prob > chi² < 0.0001

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