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Table 4 Child Health Questionnaire Parent Form 50

From: Effect of dexamethasone on quality of life in children with acute lymphoblastic leukaemia: a prospective observational study

 

T1 (n = 15)

T2 (n = 37)

 

Dexa + Mean (SD)

Dexa – Mean (SD)

Effect Size1

p2

Dexa + Mean (SD)

Dexa – Mean (SD)

Effect size1

p3

Physical Functioning

63.3# (15.0)

82.2# (13.3)

-1.26

<0.01

47.8#^(24.0)

72.4#^(23.6)

-1.03

<0.01

Role Limitations: emotional/behaviour

60.7# (33.6)

93.7 (9.5)

-0.98

0.01

41.1#^(30.2)

76.3# (25.1)

-1.17

<0.01

Role Limitations: physical

51.1# (20.4)

85.7# (14.4)

-1.70

<0.01

43.2# (25.0)

69.4# (29.5)

-0.89

<0.01

Bodily Pain

56.0# (18.4)

66.7# (16.3)

-0.58

0.05

43.8# (18.0)

64.3# (22.3)

-0.92

<0.01

General Behaviour

59.5# (16.6)

76.9 (16.9)

-1.03

0.01

55.8# (14.0)

68.9# (13.8)

-0.94

<0.01

Mental Health

59.7# (14.7)

74.7# (11.3)

-1.02

<0.01

55.3# (17.0)

68.9# (14.2)

-0.8

<0.01

Self-esteem

60.3# (15.2)

71.1# (13.4)

-0.71

0.01

54.4# (20.3)

66.3# (16.9)

-0.59

<0.01

General Health Perception

45.0# (19.1)

49.3# (12.2)

-0.23

NS

43.5# (20.8)

46.4# (21.0)

-0.14

NS

Parental Impact: emotional

54.4# (24.0)

62.8# (19.1)

-0.35

NS

50.7# (24.4)

54.3# (26.7)

-0.13

NS

Parental Impact: time

51.9# (27.1)

77.0# (17.1)

-0.93

0.01

43.8# (30.9)

60.4# (31.8)

-0.52

<0.01

Family Activities

56.3# (23.8)

75.8# (13.6)

-0.82

<0.01

41.7# (23.5)

58.6# (20.0)

-0.72

<0.01

Family Cohesion

74.7 (22.0)

75.0 (19.1)

-0.01

NS

59.2#^(23.2)

67.2 (17.4)

-0.34

<0.01

Physical Summary Score Z-score‡

30.6# (10.0)

42.2# (6.8)

-1.16

<0.01

24.3#^(11.1)

33.5# (13.2)

-0.70

<0.01

Psychosocial Summary Score Z-score‡

39.0# (11.4)

51.0 (5.1)

-1.05

0.01

34.5# (11.2)

44.4# (8.9)

-0.88

<0.01

  1. Higher scores indicate a better QoL
  2. 1 Effect size = negative effect size indicates worse QoL in the group on dexamethasone. Positive effect size indicates better QoL in the group on dexamethasone: 0.2 ≤ d < 0.5 = small effect; 0.5 ≤ d < 0.8 = moderate effect; d ≥ 0.8 = large effect.
  3. 2 Differences on and off dexamethasone, Wilcoxon signed ranks test
  4. 3 Differences on and off dexamethasone, T-test for paired samples
  5. # significant difference with Dutch reference (p < 0.05)
  6. ^Significant difference T1 vs. T2 (p < 0.05)
  7. ‡ Physical and Psychosocial CHQ summary scores based on a factor-analytical model on U.S. population samples. A score of 50 represents the mean in the general U.S. population. Scores below/above 50 are below/above the average in the general U.S. population.