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Table 5 MID estimates for EQ-5D VAS scores by ECOG grade and FACT-G quintile

From: Estimation of minimally important differences in EQ-5D utility and VAS scores in cancer

Cancer Group

Quintile FACT

FACT mean

n

Mean

SD

Median

Mean Diff

SEM

0.5 SD

0.33 SD

All

1

56.7

102

52

18

50

11

10

9

6

 

2

68.9

107

63

18

70

8

10

9

6

 

3

76.9

111

71

18

70

5

10

9

6

 

4

83.7

101

76

16

80

3

9

8

5

 

5

92.7

107

78

19

80

 

11

9

6

Mean MID

      

7

10

9

6

Lung

1

56.7

7

45

19

50

16

11

9

6

 

2

68.9

11

61

18

60

21

10

9

6

 

3

76.9

6

82

7

85

-7

4

4

2

 

4

83.7

10

75

18

75

0

10

9

6

 

5

92.7

16

75

24

80

 

14

12

8

Mean MID

      

7

10

9

6

 

ECOG Grade

         

All

0

 

122

77

19

80

8

11

10

6

 

1

 

258

69

18

70

8

10

9

6

 

2

 

133

61

20

60

3

11

10

7

 

3

 

21

57

23

50

 

13

12

8

Mean MID

      

8

11

10

6

Lung

0

 

9

80

11

80

9

6

5

4

 

1

 

29

71

16

75

17

9

8

5

 

2

 

11

54

17

69

24

10

9

6

 

3

 

1

30

 

30

    

Mean MID

      

12

9

8

5

  1. ECOG – Eastern Cancer Oncology Group (grade ranges from level 0 is fully active to level 3, capable of only limited self-care and confined to bed more than 50% of waking hours); MID – minimally important difference; SEM – standard error of the mean; SD – standard deviation