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Table 5 MID estimates for EQ-5D VAS scores by ECOG grade and FACT-G quintile

From: Estimation of minimally important differences in EQ-5D utility and VAS scores in cancer

Cancer Group Quintile FACT FACT mean n Mean SD Median Mean Diff SEM 0.5 SD 0.33 SD
All 1 56.7 102 52 18 50 11 10 9 6
  2 68.9 107 63 18 70 8 10 9 6
  3 76.9 111 71 18 70 5 10 9 6
  4 83.7 101 76 16 80 3 9 8 5
  5 92.7 107 78 19 80   11 9 6
Mean MID        7 10 9 6
Lung 1 56.7 7 45 19 50 16 11 9 6
  2 68.9 11 61 18 60 21 10 9 6
  3 76.9 6 82 7 85 -7 4 4 2
  4 83.7 10 75 18 75 0 10 9 6
  5 92.7 16 75 24 80   14 12 8
Mean MID        7 10 9 6
  ECOG Grade          
All 0   122 77 19 80 8 11 10 6
  1   258 69 18 70 8 10 9 6
  2   133 61 20 60 3 11 10 7
  3   21 57 23 50   13 12 8
Mean MID        8 11 10 6
Lung 0   9 80 11 80 9 6 5 4
  1   29 71 16 75 17 9 8 5
  2   11 54 17 69 24 10 9 6
  3   1 30   30     
Mean MID        12 9 8 5
  1. ECOG – Eastern Cancer Oncology Group (grade ranges from level 0 is fully active to level 3, capable of only limited self-care and confined to bed more than 50% of waking hours); MID – minimally important difference; SEM – standard error of the mean; SD – standard deviation