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Table 4 Odds ratios and % mediation for selected HUI3 attributes in the chronic condition subsamples

From: Physical activity as a mediator of the impact of chronic conditions on quality of life in older adults

  HUI3 attributes (dependent variables)
Independent variables Dexterity
OR (95% CI)
Emotional wellbeing
OR (95% CI)
Cognition
OR (95% CI)
Pain
OR (95% CI)
Mobility
OR (95% CI)
Musculoskeletal disorders versus no chronic condition (n = 14,112)1 11.0 (4.3 – 28.5) 4.7 (2.9 – 7.6) 2.2 (2.0 – 2.5) 12.0 (9.0 – 16.1) 6.6 (4.8 – 9.0)
Physical activity < 1,000 Kcal/week2 1.5 (1.0 – 2.3) 2.3 (1.6 – 3.3) 1.1 (1.0 – 1.3) 1.4 (1.2 – 1.7) 3.7 (3.0 – 4.5)
   % mediation3 5% 13%* 4% 4%* 16%*
Respiratory disorders versus no chronic condition (n = 5,361)1 10.4 (3.7 – 28.9) 5.0 (3.0 – 8.1) 2.2 (1.8 – 2.6) 10.7 (8.0 – 14.5) 7.6 (5.4 – 10.7)
Physical activity < 1,000 Kcal/week2 0.8 (0.4 – 1.5) 2.0 (0.9 – 4.5) 1.2 (1.0 – 1.5) 1.4 (1.0 – 1.8) 3.9 (2.5 – 6.0)
   % mediation3 0% 20% 13% 7% 27%*
Cardiovascular disorders versus no chronic condition (n = 13,380)1 7.8 (3.0 – 20.0) 4.0 (2.5 – 6.4) 1.9 (1.7 – 2.2) 7.2 (5.4 – 9.5) 5.6 (4.1 – 7.7)
Physical activity < 1,000 Kcal/week2 1.4 (0.9 – 2.2) 2.1 (1.4 – 3.2) 1.2 (1.0 – 1.3) 1.6 (1.3 – 1.9) 3.3 (2.6 – 4.1)
   % mediation3 5% 16%* 7% 8%* 19%*
Diabetes versus no chronic condition (n = 5,393)1 10.6 (4.3 – 26.5) 5.0 (3.0 – 8.5) 1.9 (1.6 – 2.3) 7.1 (5.2 – 9.7) 6.6 (4.8 – 9.2)
Physical activity < 1,000 Kcal/week2 1.2 (0.5 – 3.1) 1.9 (0.8 – 4.1) 1.2 (1.0 – 1.5) 1.7 (1.3 – 2.3) 3.5 (2.3 – 5.3)
   % mediation3 3% 13% 10% 10%* 21%*
"Suffering the effects of a stroke" versus no chronic condition (n = 3,533)1 24.9 (7.9 – 78.1) 9.4 (5.1 – 17.5) 3.4 (2.7 – 4.3) 12.4 (8.7 – 17.7) 18.2 (12.7 – 26.1)
Physical activity < 1,000 Kcal/week2 0.6 (0.2 – 2.4) 1.2 (0.4 – 3.6) 1.0 (0.8 – 1.4) 1.3 (0.8 – 2.0) 2.6 (1.5 – 4.6)
   % mediation3 0% 5% 3% 7% 20%*
Urinary or bowel disorders versus no chronic condition (n = 5,038)1 15.3 (5.8 – 40.5) 7.7 (4.5 – 13.1) 3.1 (2.6 – 3.8) 14.4 (10.5 – 19.7) 9.9 (7.1 – 13.9)
Physical activity < 1,000 Kcal/week2 1.0 (0.6 – 1.8) 1.2 (0.7 – 2.1) 1.1 (0.9 – 1.4) 2.0 (1.5 – 2.7) 2.9 (2.0 – 4.2)
   % mediation3 0% 4% 6% 12%* 20%*
  1. All odds ratios are adjusted for age, sex, cigarette use, alcohol consumption, and obesity. The reference groups for the HUI3 attributes are the same as in Table 2.
  2. 1 Referent = no chronic condition.
  3. 2 Referent = ≥ 1,000 Kcal/week.
  4. 3 Percentage of the total effect that is attributable to the mediating effect of physical activity.
  5. * Statistically significant indirect effects (p < 0.01).