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Table 4 Mean Migraine-Specific Questionnaire (MSQ) and Medical Outcome Study Short Form 36 (SF-36) scores at baseline for pooled intent-to-treat (ITT) subjects with < 50% and ≥ 50% reductions in monthly migraine frequency, regardless of study medication*

From: The impact of migraine prevention on daily activities: a longitudinal and responder analysis from three topiramate placebo-controlled clinical trials

 

< 50% Responders

≥ 50% Responders

MSQ Domain

n

Baseline

n

Baseline

Emotional Function

455

55.5

244

55.2

Role Prevention

454

68.3

243

67.0

Role Restriction

455

50.1

244

49.4

SF-36 Subscale

n

Baseline

n

Baseline

Physical Functioning

454

83.1

243

80.3

Bodily Pain

453

51.4

244

51.6

Vitality

454

51.7

243

50.0

General Health

447

68.4

242

68.3

Role-Emotional

453

71.0

240

68.2

Role Physical

452

44.6

241

44.1

Mental Health

454

71.3

243

70.7

Social Functioning

455

69.8

244

68.6

Physical Component Score

439

43.2

237

42.8

Mental Component Score

439

47.4

237

46.9

  1. *N values reflect the numbers of patients with evaluable data on each domain, not the ITT population.