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Table 4 CD4 and Viral Load Adjusted Incidence Rate Ratios (IRRs) for Hospital Discharge Rate in Poisson Models

From: EuroQol (EQ-5D) measure of quality of life predicts mortality, emergency department utilization, and hospital discharge rates in HIV-infected adults under care

Measure1

Adjusted3

 

IRR

95% CI

p-value

Mobility

  

<0.001

No problems

1.0

  

Some problems

2.3

2.0–2.8

<0.001

Confined to bed

2.9

2.1–4.0

<0.001

Self-Care

  

<0.001

No problems

1.0

  

Some problems

2.1

1.8–2.4

<0.001

Unable to wash or dress

2.3

1.7–3.2

<0.001

Usual Activities

  

<0.001

No problems

1.0

  

Some problems

2.2

1.9–2.7

<0.001

Unable to perform

3.5

2.7–4.5

<0.001

Pain/Discomfort

  

<0.001

None

1.0

  

Moderate

1.9

1.6–2.3

<0.001

Extreme

3.1

2.4–3.9

<0.001

Anxiety/Depression

  

0.01

None

1.0

  

Moderate

1.1

0.9–1.3

0.31

Extreme

1.4

1.1–1.8

0.002

VAS 2 (per 10 units)

0.85

0.82–0.88

<0.001

pVAS (per 10 units)

0.79

0.75–0.82

<0.001

Health change

  

<0.001

Better

1.0

  

Much the same

1.2

1.0–1.5

0.032

Worse

2.0

1.6–2.5

<0.001

  1. 1. Items 1–5 (Mobility, Self Care, Usual Activities, Pain/Discomfort, Anxiety/Depression) are EQ-5D health states. Health change is not part of EQ-5D. EQ-5D health states, VAS, health change, CD4 category, and HIV-1 plasma viral load are modelled as time-varying covariates.
  2. 2. EQ-5D Visual Analog Scale (VAS) rating of global health status (0–100); pVAS (predicted VAS; see Methods)
  3. 3. Each covariate is adjusted only for CD4 category (<50, 50–199, ≥200) and plasma HIV-1 viral load (<1,000, ≥1,000 copies), not for the other listed health status items. CD4 category and plasma HIV-1 viral load are modelled as time-varying covariates.
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Health and Quality of Life Outcomes

ISSN: 1477-7525

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