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Table 4 Child Self-Report: Means and Standard Deviations for the PedsQL™ 4.0 Generic Core Scales by Disease Category.

From: Impaired health-related quality of life in children and adolescents with chronic conditions: a comparative analysis of 10 disease clusters and 33 disease categories/severities utilizing the PedsQL™ 4.0 Generic Core Scales

   Total Score Physical Health Psychosocial Health Emotional Functioning Social Functioning School Functioning
  n Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD)
Asthma        
Mild Intermittenta 75 81.25 (12.68) 85.80 (16.81) 78.99 (14.58) 75.08 (19.24) 83.44 (21.60) 79.67 (20.15)
Mild Persistentb 28 73.71 (12.51) 77.95 (16.40) 71.61 (14.64) 70.09 (17.04) 78.12 (19.20) 67.26 (22.90)
Moderate to Severe Persistent c 23 59.64 (21.56) 59.57 (23.50) 59.76 (23.09) 49.18 (27.59) 70.65 (27.28) 61.93 (32.74)
Differences   a > c***; b > c** a > c***; b > c** a > c***; b > c* a > c***; b > c** a > c* a > b*; a > c**
Cancer        
Acute Lymphoblastic Leukemiaa 109 73.25 (16.78) 74.16 (20.59) 72.86 (17.12) 72.57 (22.98) 76.90 (20.11) 68.67 (19.88)
Brain Tumor b 194 71.04 (16.05) 71.29 (21.05) 71.02 (16.50) 72.32 (20.17) 73.00 (22.57) 67.84 (19.67)
Newly Diagnosed On-Treatment¤ 105 68.92 (15.97) 65.54 (23.14) 71.04 (15.17) 68.81 (21.24) 77.19 (18.29) 66.22 (19.60)
Long-Term Survivor Off-Treatment > 12 months§ 72 77.50 (15.30) 79.95 (18.78) 76.30 (16.04) 77.57 (20.31) 79.36 (19.77) 71.11 (18.11)
Differences   § > ¤*** § > ¤*** § > ¤* § > ¤** _____ _____
Cardiac        
Disease Severity Group 1 a 52 82.67 (13.98) 87.97 (13.46) 79.82 (16.28) 76.15 (21.95) 83.46 (19.24) 79.31 (16.28)
Disease Severity Group 2 b 92 76.30 (13.89) 81.45 (15.30) 73.56 (14.73) 72.09 (17.40) 77.80 (18.22) 70.82 (19.45)
Disease Severity Group 3 c 63 76.36 (15.48) 80.82 (15.66) 73.92 (18.21) 72.46 (20.79) 77.92 (21.80) 71.43 (21.30)
Disease Severity Group 4 d 78 75.81 (13.93) 78.42 (17.69) 74.41 (15.01) 74.68 (21.02) 77.66 (19.03) 70.96 (18.15)
Differences   a > d* a > d** _____ _____ _____ _____
Cerebral Palsy        
Hemiplegiaa 30 73.14 (12.81) 75.41 (16.97) 71.78 (13.83) 72.80 (23.43) 73.00 (17.40) 70.56 (17.02)
Diplegiab 29 68.71 (16.55) 63.95 (19.66) 71.17 (17.12) 72.50 (20.75) 73.10 (20.76) 67.93 (24.04)
Paraplegiac 11 53.86 (12.21) 45.70 (16.55) 58.20 (14.42) 57.73 (16.64) 60.00 (17.89) 57.27 (21.84)
Differences   a > c**; b > c* a > b*; a > c***;b > c* a > c* _____ _____ _____
Diabetes        
Type 1 a 209 81.64 (12.44) 86.66 (13.21) 78.90 (14.09) 73.99 (19.49) 86.42 (15.81) 76.59 (16.68)
Type 2 b 88 77.46 (13.68) 84.36 (13.62) 73.75 (15.52) 68.69 (19.54) 83.47 (17.29) 68.97 (20.23)
Differences   a > b* _____ a > b** a > b* _____ a > b**
End Stage Renal Disease        
Transplanta 39 78.94 (14.24) 80.76 (20.53) 77.86 (13.46) 79.04 (18.70) 82.31 (17.54) 72.31 (16.13)
Peritoneal Dialysisb 15 70.70 (16.53) 72.89 (15.33) 69.69 (18.66) 68.75 (22.74) 73.50 (24.38) 66.25 (18.28)
Hemodialysisc 31 69.30 (14.29) 68.04 (20.74) 69.95 (13.29) 73.39 (16.45) 76.01 (13.46) 60.48 (21.46)
Differences   a > c* a > c* _____ _____ _____ _____
Gastrointestinal Conditions        
Irritable Bowel Syndromea 119 77.90 (12.64) 80.49 (13.23) 76.50 (13.81) 74.93 (17.43) 84.09 (15.43) 70.59 (18.70)
Functional Abdominal Painb 81 79.98 (10.62) 82.83 (11.29) 78.46 (12.10) 75.49 (17.06) 86.17 (13.28) 73.70 (15.96)
Organic Disordersc 80 75.41 (16.01) 79.21 (16.70) 73.39 (17.60) 70.94 (21.93) 82.81 (18.40) 66.39 (20.23)
Differences   _____ _____ _____ _____ _____ b > c*
Obesity        
Severely Obesea 106 67.00 (16.30) 71.00 (18.80) 64.90 (17.70) 63.20 (20.10) 67.50 (25.00) 64.10 (20.40)
Obeseb 63 74.00 (14.20) 77.50 (17.90) 72.10 (14.10) 68.60 (18.50) 72.60 (18.20) 75.00 (14.50)
Overweightc 294 79.30 (12.80) 83.50 (13.00) 77.00 (14.00) 72.60 (17.70) 80.20 (16.60) 78.30 (15.50)
Differences   b > a**; c > a***; c > b** c > b**; c > a***; b > a* b > a**; c > a***; c > b* c > a*** c > a***; c > b** c > a***; b > a**
Psychiatric Disorders        
Attention-Deficit and Disruptive Behavior Disordersa 107 72.40 (12.20) 84.30 (13.20) 66.00 (14.70) 61.30 (19.50) 70.30 (21.40) 66.40 (16.20)
Anxiety Disordersb 57 71.30 (12.20) 78.60 (15.60) 67.40 (13.60) 59.00 (17.70) 74.40 (19.50) 68.90 (13.90)
Mood Disorders c 29 69.70 (13.10) 80.00 (13.30) 64.20 (15.00) 55.50 (21.70) 74.40 (22.00) 63.90 (16.40)
Pervasive Developmental Disorders d 28 69.60 (14.00) 78.50 (14.30) 64.80 (16.60) 63.80 (17.40) 63.10 (23.00) 67.60 (20.50)
Differences   _____ _____ _____ _____ _____ _____
Rheumatology        
Systemic Lupus Erythematosusa 29 76.95 (14.97) 76.13 (19.81) 77.46 (15.69) 70.65 (23.70) 89.44 (14.29) 73.52 (16.63)
Spondyloarthritisb 39 74.92 (18.41) 69.24 (25.10) 77.99 (17.07) 77.27 (22.24) 84.87 (19.54) 72.18 (20.96)
Juvenile Rheumatoid Arthritisc 100 73.73 (16.47) 70.88 (21.52) 75.18 (16.65) 73.13 (20.87) 78.64 (19.61) 74.27 (19.07)
Fibromyalgiad 57 55.86 (15.16) 45.40 (19.86) 61.44 (16.25) 53.77 (22.41) 74.47 (18.21) 55.74 (20.46)
Differences   a, b, c > d*** a, b, c > d*** a, b, c > d*** b, c > d***; a > d* a > d** c > d***; a, b > d**
  1. Note: *p < .05, **p < .01, ***p < .001 based on Tukey post-hoc analysis when more than 2 disease categories are being compared and independent samples t-test when 2 disease categories are being compared. Contrasts for cancer disease categories are for Acute Lymphoblastic Leukemiaa versus Brain Tumorband Newly Diagnosed On-Treatment ¤ versus Long Term Survivor Off-Treatment > 12 months §. Asthma contrasts are based on the PedsQL™ 4.0 SF15, a shorted version of the 23-item PedsQL™ 4.0 Generic Core Scales.