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Table 4 Child Self-Report: Means and Standard Deviations for the PedsQL™ 4.0 Generic Core Scales by Disease Category.

From: Impaired health-related quality of life in children and adolescents with chronic conditions: a comparative analysis of 10 disease clusters and 33 disease categories/severities utilizing the PedsQL™ 4.0 Generic Core Scales

  

Total Score

Physical Health

Psychosocial Health

Emotional Functioning

Social Functioning

School Functioning

 

n

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Asthma

       

Mild Intermittenta

75

81.25 (12.68)

85.80 (16.81)

78.99 (14.58)

75.08 (19.24)

83.44 (21.60)

79.67 (20.15)

Mild Persistentb

28

73.71 (12.51)

77.95 (16.40)

71.61 (14.64)

70.09 (17.04)

78.12 (19.20)

67.26 (22.90)

Moderate to Severe Persistent c

23

59.64 (21.56)

59.57 (23.50)

59.76 (23.09)

49.18 (27.59)

70.65 (27.28)

61.93 (32.74)

Differences

 

a > c***; b > c**

a > c***; b > c**

a > c***; b > c*

a > c***; b > c**

a > c*

a > b*; a > c**

Cancer

       

Acute Lymphoblastic Leukemiaa

109

73.25 (16.78)

74.16 (20.59)

72.86 (17.12)

72.57 (22.98)

76.90 (20.11)

68.67 (19.88)

Brain Tumor b

194

71.04 (16.05)

71.29 (21.05)

71.02 (16.50)

72.32 (20.17)

73.00 (22.57)

67.84 (19.67)

Newly Diagnosed On-Treatment¤

105

68.92 (15.97)

65.54 (23.14)

71.04 (15.17)

68.81 (21.24)

77.19 (18.29)

66.22 (19.60)

Long-Term Survivor Off-Treatment > 12 months§

72

77.50 (15.30)

79.95 (18.78)

76.30 (16.04)

77.57 (20.31)

79.36 (19.77)

71.11 (18.11)

Differences

 

§ > ¤***

§ > ¤***

§ > ¤*

§ > ¤**

_____

_____

Cardiac

       

Disease Severity Group 1 a

52

82.67 (13.98)

87.97 (13.46)

79.82 (16.28)

76.15 (21.95)

83.46 (19.24)

79.31 (16.28)

Disease Severity Group 2 b

92

76.30 (13.89)

81.45 (15.30)

73.56 (14.73)

72.09 (17.40)

77.80 (18.22)

70.82 (19.45)

Disease Severity Group 3 c

63

76.36 (15.48)

80.82 (15.66)

73.92 (18.21)

72.46 (20.79)

77.92 (21.80)

71.43 (21.30)

Disease Severity Group 4 d

78

75.81 (13.93)

78.42 (17.69)

74.41 (15.01)

74.68 (21.02)

77.66 (19.03)

70.96 (18.15)

Differences

 

a > d*

a > d**

_____

_____

_____

_____

Cerebral Palsy

       

Hemiplegiaa

30

73.14 (12.81)

75.41 (16.97)

71.78 (13.83)

72.80 (23.43)

73.00 (17.40)

70.56 (17.02)

Diplegiab

29

68.71 (16.55)

63.95 (19.66)

71.17 (17.12)

72.50 (20.75)

73.10 (20.76)

67.93 (24.04)

Paraplegiac

11

53.86 (12.21)

45.70 (16.55)

58.20 (14.42)

57.73 (16.64)

60.00 (17.89)

57.27 (21.84)

Differences

 

a > c**; b > c*

a > b*; a > c***;b > c*

a > c*

_____

_____

_____

Diabetes

       

Type 1 a

209

81.64 (12.44)

86.66 (13.21)

78.90 (14.09)

73.99 (19.49)

86.42 (15.81)

76.59 (16.68)

Type 2 b

88

77.46 (13.68)

84.36 (13.62)

73.75 (15.52)

68.69 (19.54)

83.47 (17.29)

68.97 (20.23)

Differences

 

a > b*

_____

a > b**

a > b*

_____

a > b**

End Stage Renal Disease

       

Transplanta

39

78.94 (14.24)

80.76 (20.53)

77.86 (13.46)

79.04 (18.70)

82.31 (17.54)

72.31 (16.13)

Peritoneal Dialysisb

15

70.70 (16.53)

72.89 (15.33)

69.69 (18.66)

68.75 (22.74)

73.50 (24.38)

66.25 (18.28)

Hemodialysisc

31

69.30 (14.29)

68.04 (20.74)

69.95 (13.29)

73.39 (16.45)

76.01 (13.46)

60.48 (21.46)

Differences

 

a > c*

a > c*

_____

_____

_____

_____

Gastrointestinal Conditions

       

Irritable Bowel Syndromea

119

77.90 (12.64)

80.49 (13.23)

76.50 (13.81)

74.93 (17.43)

84.09 (15.43)

70.59 (18.70)

Functional Abdominal Painb

81

79.98 (10.62)

82.83 (11.29)

78.46 (12.10)

75.49 (17.06)

86.17 (13.28)

73.70 (15.96)

Organic Disordersc

80

75.41 (16.01)

79.21 (16.70)

73.39 (17.60)

70.94 (21.93)

82.81 (18.40)

66.39 (20.23)

Differences

 

_____

_____

_____

_____

_____

b > c*

Obesity

       

Severely Obesea

106

67.00 (16.30)

71.00 (18.80)

64.90 (17.70)

63.20 (20.10)

67.50 (25.00)

64.10 (20.40)

Obeseb

63

74.00 (14.20)

77.50 (17.90)

72.10 (14.10)

68.60 (18.50)

72.60 (18.20)

75.00 (14.50)

Overweightc

294

79.30 (12.80)

83.50 (13.00)

77.00 (14.00)

72.60 (17.70)

80.20 (16.60)

78.30 (15.50)

Differences

 

b > a**; c > a***; c > b**

c > b**; c > a***; b > a*

b > a**; c > a***; c > b*

c > a***

c > a***; c > b**

c > a***; b > a**

Psychiatric Disorders

       

Attention-Deficit and Disruptive Behavior Disordersa

107

72.40 (12.20)

84.30 (13.20)

66.00 (14.70)

61.30 (19.50)

70.30 (21.40)

66.40 (16.20)

Anxiety Disordersb

57

71.30 (12.20)

78.60 (15.60)

67.40 (13.60)

59.00 (17.70)

74.40 (19.50)

68.90 (13.90)

Mood Disorders c

29

69.70 (13.10)

80.00 (13.30)

64.20 (15.00)

55.50 (21.70)

74.40 (22.00)

63.90 (16.40)

Pervasive Developmental Disorders d

28

69.60 (14.00)

78.50 (14.30)

64.80 (16.60)

63.80 (17.40)

63.10 (23.00)

67.60 (20.50)

Differences

 

_____

_____

_____

_____

_____

_____

Rheumatology

       

Systemic Lupus Erythematosusa

29

76.95 (14.97)

76.13 (19.81)

77.46 (15.69)

70.65 (23.70)

89.44 (14.29)

73.52 (16.63)

Spondyloarthritisb

39

74.92 (18.41)

69.24 (25.10)

77.99 (17.07)

77.27 (22.24)

84.87 (19.54)

72.18 (20.96)

Juvenile Rheumatoid Arthritisc

100

73.73 (16.47)

70.88 (21.52)

75.18 (16.65)

73.13 (20.87)

78.64 (19.61)

74.27 (19.07)

Fibromyalgiad

57

55.86 (15.16)

45.40 (19.86)

61.44 (16.25)

53.77 (22.41)

74.47 (18.21)

55.74 (20.46)

Differences

 

a, b, c > d***

a, b, c > d***

a, b, c > d***

b, c > d***; a > d*

a > d**

c > d***; a, b > d**

  1. Note: *p < .05, **p < .01, ***p < .001 based on Tukey post-hoc analysis when more than 2 disease categories are being compared and independent samples t-test when 2 disease categories are being compared. Contrasts for cancer disease categories are for Acute Lymphoblastic Leukemiaa versus Brain Tumorband Newly Diagnosed On-Treatment ¤ versus Long Term Survivor Off-Treatment > 12 months §. Asthma contrasts are based on the PedsQL™ 4.0 SF15, a shorted version of the 23-item PedsQL™ 4.0 Generic Core Scales.