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Table 3 Proxy-Report: Means and Standard Deviations for the PedsQL™ 4.0 Generic Core Scales by Disease Cluster and Comparisons with Healthy Children Scores.

From: Impaired health-related quality of life in children and adolescents with chronic conditions: a comparative analysis of 10 disease clusters and 33 disease categories/severities utilizing the PedsQL™ 4.0 Generic Core Scales

 

Healthya

Card.b

Diab.c

Obesityd

GIe

ESRDf

Asthmag

Rheum.h

Canceri

Psych.j

CPk

 

Scale

Mean (SD)

Mean (SD) ES

Mean (SD) ES

Mean (SD) ES

Mean (SD) ES

Mean (SD) ES

Mean (SD) ES

Mean (SD) ES

Mean (SD) ES

Mean (SD) ES

Mean (SD) ES

Differences

Proxy-Report

(n = 9430)

(n = 344)

(n = 307)

(n = 63)

(n = 286)

(n = 95)

(n = 157)

(n = 357)

(n = 561)

(n = 307)

(n = 224)

 

Total Score

82.70 (15.40)

79.44 (16.50) 0.21

76.62 (14.08) 0.39

75.00 (14.50) 0.50

72.74 (14.75) 0.65

69.62 (18.10) 0.82

68.79 (15.94) 0.90

68.73 (19.32) 0.91

68.47 (19.22) 0.92

66.90 (14.00) 1.03

51.28 (18.00) 2.04

a > c, g, f, j, i, h, k, d, e***; a > b**; c, b, e > j***; c > g, i, h, k***; c > f**; b > g, f, i, h, k***; g, f, j, i, h, d, e > k***; b > e***; e > h*; d > j**

Physical Health

84.48 (19.51)

83.11 (18.73) 0.07

82.02 (17.20) 0.13

76.30 (17.60) 0.42

76.00 (16.96) 0.43

71.21 (24.24) 0.68

72.68 (18.39) 0.60

64.05 (25.01) 1.05

67.55 (25.07) 0.87

80.00 (17.70) 0.23

43.19 (27.59) 2.12

a > j, d**; a > g, f, i, h, k, e***; j > g, f**; j, e > i, h, k***; b, c > g, f, i, h, k***; g > h, k***; f > h*; f, i, h > k***; c > e*; b > e***; d > h, k***; d > i*

Psychosocial Health

81.65 (15.22)

77.36 (17.27) 0.28

73.67 (15.34) 0.52

73.90 (15.30) 0.51

71.00 (15.58) 0.70

68.85 (17.62) 0.84

66.83 (16.68) 0.97

71.27 (18.49) 0.68

69.12 (18.41) 0.82

59.90 (15.30) 1.43

55.91 (16.98) 1.69

a > b, c, g, f, j, i, h, k, e***; a > d**; b, c, g, f, i, h > j***; c > i**; c > g, k***; b > g, f, i, h, k***; g, f, i, h > k***; e > j, k***; b > e***; d > j, k***

Emotional Functioning

81.31 (16.50)

74.69 (20.45) 0.40

69.16 (18.54) 0.74

72.60 (17.80) 0.53

65.19 (19.28) 0.98

68.74 (19.69) 0.76

64.81 (20.21) 1.00

66.52 (22.27) 0.90

67.57 (20.70) 0.83

54.40 (18.70) 1.63

62.73 (19.55) 1.13

a > b, c, g, f, j, i, h, k, d, e***; b, c, g, f, i, h, k, d, e > j***; b > c**; c > k**; b > g***; b > i, h, k***; i > k*; b > e***; d > k**

Social Functioning

83.70 (19.43)

82.52 (20.11) 0.06

81.08 (19.33) 0.13

73.50 (17.30) 0.52

80.30 (18.08) 0.17

73.47 (21.00) 0.53

73.41 (18.66) 0.53

76.47 (20.56) 0.37

72.80 (22.29) 0.56

63.30 (22.90) 1.05

52.09 (21.97) 1.63

a > g, f, j, i, h, k, d***; b, c, g, f, i, h > j***; c > i, k***; c > g**; c > f*; b > g, i, k***; b > f, h**; g, f, i, h, d > k***; j > k***; e > j, i, k***; e > g*; d > j**; b > d**

School Functioning

78.83 (19.59)

73.09 (20.35) 0.29

70.62 (19.37) 0.42

76.60 (17.00) 0.11

67.44 (20.06) 0.58

63.18 (21.39) 0.80

62.36 (20.61) 0.84

70.61 (22.43) 0.42

66.16 (23.33) 0.65

62.40 (18.20) 0.84

51.98 (21.41) 1.37

a > b, c, g, f, j, i, h, k, e***; b, c, h > j***; b, c, g, f, j, i, h, d, e > k***; c > g**; c > f*; b > g, i***; b > f**; h > g***; h > f, i*; b, d > e*; d > g, j***; d > f**

  1. Note: *p < .05, **p < .01, ***p < .001 based on analysis of variance with Tukey post-hoc tests.
  2. With a Bonferroni correction for the number of comparisons, p < .005 values should be considered statistically significant.
  3. Higher values equal better health-related quality of life. Disease clusters are ordered from left to right by decreasing overall HRQOL.
  4. ES equals effect size.
  5. Effect size represents the magnitude in the difference between the disease cluster and the healthy children sample.
  6. Effect sizes are designated as small (.20), medium (.50), and large (.80).
  7. Diabetes. Card. equals Cardiac. ESRD equals End Stage Renal Disease. Psych. equals Psychiatric Disorders s Rheumatology. CP equals Cerebral Palsy. GI equals Gastrointestinal Conditions.