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Table 3 Predictors of MSQoL-54 composite scores by IFN-β treatment (Multivariate hierarchical analysis)

From: Influence of Interferon beta treatment on quality of life in multiple sclerosis patients

 

Physical Health Composite Score

Mental Health Composite Score

Effect

β

p

β

p

Intercept*

65.08

<.0001

69.31

<.0001

Age at inclusion

-0.19

0.043

-0.22

0.06

Gender (Male vs. Female)

-1.51

0.43

-6.95

0.005

Disease duration

-0.1

0.41

-0.04

0.82

Disease course (SP vs. RR)

3.69

0.24

8.39

0.037

Relapse rate 2-yrs before study entry

0.69

0.75

0.62

0.83

EDSS

-3.44

0.0003

-0.85

0.47

BDI

-0.59

<.0001

-1.44

<.0001

FSS

-6.69

<.0001

-2.08

0.019

MMSE-c

-0.28

0.44

0.45

0.34

IFN-β treatment (Yes vs No)

-0.09

0.97

2.75

0.36

Relapse rate change after 2-yrs

2.15

0.42

0.60

0.84

EDSS change after 2-yrs

-1.57

0.26

1.59

0.31

BDI change after 2-yrs

-0.60

<.0001

-1.08

<.0001

FSS change after 2-yrs

-5.21

<.0001

-2.48

0.01

MMSE-c change after 2-yrs

-0.35

0.53

-0.16

0.81

Time**

1.32

0.54

3.33

0.19

Time × IFN-β treatment (Yes vs No)

-1.65

0.58

-9.19

0.01

  1. *Intercept value represents the baseline mean score for reference group (Untreated)
  2. **Time value represents the mean score change for reference group (Untreated) after 2 years of follow-up