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Table 3 Predictors of MSQoL-54 composite scores by IFN-β treatment (Multivariate hierarchical analysis)

From: Influence of Interferon beta treatment on quality of life in multiple sclerosis patients

  Physical Health Composite Score Mental Health Composite Score
Effect β p β p
Intercept* 65.08 <.0001 69.31 <.0001
Age at inclusion -0.19 0.043 -0.22 0.06
Gender (Male vs. Female) -1.51 0.43 -6.95 0.005
Disease duration -0.1 0.41 -0.04 0.82
Disease course (SP vs. RR) 3.69 0.24 8.39 0.037
Relapse rate 2-yrs before study entry 0.69 0.75 0.62 0.83
EDSS -3.44 0.0003 -0.85 0.47
BDI -0.59 <.0001 -1.44 <.0001
FSS -6.69 <.0001 -2.08 0.019
MMSE-c -0.28 0.44 0.45 0.34
IFN-β treatment (Yes vs No) -0.09 0.97 2.75 0.36
Relapse rate change after 2-yrs 2.15 0.42 0.60 0.84
EDSS change after 2-yrs -1.57 0.26 1.59 0.31
BDI change after 2-yrs -0.60 <.0001 -1.08 <.0001
FSS change after 2-yrs -5.21 <.0001 -2.48 0.01
MMSE-c change after 2-yrs -0.35 0.53 -0.16 0.81
Time** 1.32 0.54 3.33 0.19
Time × IFN-β treatment (Yes vs No) -1.65 0.58 -9.19 0.01
  1. *Intercept value represents the baseline mean score for reference group (Untreated)
  2. **Time value represents the mean score change for reference group (Untreated) after 2 years of follow-up