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Table 1 Characteristics of included studies

From: Combining scores from different patient reported outcome measures in meta-analyses: when is it justified?

Study groups

Number of patients

Intervention

Wks of follow-up

Study design

Mean baseline scores (SD)

Mean change scores (SD)

Order of questionnaires randomized

Use of validated questionnaires

     

CRQ

SGRQ

CRQ

SGRQ

  

Barr [18]

102

Respiratory rehabilitation (RP)

4

Prospective follow-up study

3.89 (0.89)

55.8 (17.9)

0.71 (0.75)

-3.00 (12.20)

No

Yes

Bestall [14]

23

RP

52

RCT

4.00 (0.90)

51.0 (13.7)

0.35 (0.85)

-3.00 (12.20)

No

Yes

Bestall [14]

21

Patient education

52

RCT

4.28 (0.98)

51.9 (13.9)

-0.05 (0.58)

-1.00 (9.35)

No

Yes

Bourbeau [22]

65

RP

2

Prospective follow-up study

n.a.

n.a.

0.74 (0.74)

-7.20 (12.30)

Yes

Yes

Bourbeau [22]

27

Usual care

2

Prospective follow-up study

n.a.

n.a.

0.35 (0.31)

-2.40 (5.57)

Yes

Yes

Connor [16]

170

RP

52

Prospective follow-up study

n.a.

51.6 (15.8)

n.a.

n.a.

No

Yes

Desikan [23]

40

Usual care

12

Prospective follow-up study

3.75 (0.95)

50.2 (18.5)

0.33 (0.86)

-2.51 (9.71)

Yes

Yes

de Torres [19]

37

RP

8

Prospective follow-up study

4.13 (0.95)

52.0 (13.0)

0.56 (1.20)

-4.00 (13.40)

No

Yes

Griffiths [20]

37

RP

52

RCT

3.59 (0.95)

64.9 (12.7)

0.25 (0.80)

-3.40 10.86)

No

Yes

Griffiths [20]

33

Usual care

52

RCT

3.53 (0.95)

68.3 (13.3)

-0.08 (0.80)

0.70 (10.86)

No

Yes

Hajiro [24]

165

Usual care

12

Prospective follow-up study

5.31 (0.97)

40.3 (20.1)

0.65 (0.83)

-6.00 (18.50)

No

Yes

Harper [25]

156

Usual care

26

Prospective follow-up study

3.69 (0.95)

65.4 (15.9)

0.07 (1.00)

0.81 (9.95)

No

Yes

Man [17]

21

RP

18

RCT

2.64 (0.95)

65.4 (13.5)

1.87 (0.53)

-16.10 (5.95)

No

Yes

Man [17]

21

Usual care

16

RCT

3.11 (0.95)

69.6 (13.6)

0.49 (0.26)

-3.40 (8.50)

No

Yes

Rutten [9]

47

Salmeterol + Ipratropium

12

RCT

4.44 (0.81)

48.3 (13.9)

0.20 (0.60)

-2.40 (11.00)

No

Yes

Rutten [9]

47

Salmeterol + Placebo

12

RCT

4.58 (1.03)

50.5 (16.6)

-0.19 (0.80)

-0.01 (7.10)

No

Yes

Rutten [9]

50

Placebo

12

RCT

4.22 (1.05)

50.2 (15.8)

0.03 (0.70)

0.50 (9.20)

No

Yes

Singh [12]

97

RP

7

Prospective follow-up study

3.66 (0.92)

58.8 (15.2)

0.72 (1.00)

-4.02 (12.98)

No

Yes

Schunemann [8]

84

RP

12

Prospective follow-up study

4.01 (0.95)

52.8 (13.9)

1.14 (0.90)

-8.10 (20.40)

Yes

Yes

Schunemann [10]

183

RP

12

Prospective follow-up study

4.57 (0.95)

50.6 (13.9)

0.55 (0.89)

-5.43 (11.18)

Yes

Yes

Wedzicha [15]

26

RP on

8

RCT

3.76 (0.90)

56.7 (14.0)

0.20 (0.39)

3.00 (10.40)

No

Yes

Wedzicha [15]

28

Patient education

8

RCT

3.82 (1.20)

59.1 (13.0)

0.20 (0.32)

2.00 (8.10)

No

Yes

  1. RCT: Randomized controlled trial; n.a.: not available