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Table 8 Responsiveness statistics and relative ranking of selected HRQL measures according to change on the external criterion: Six-Minute Walk Test

From: Assessing responsiveness of generic and specific health related quality of life measures in heart failure

6 Minute Walk – Deteriorated <= -200 n T-Statistic (Rank) Effect Size (Rank) Guyatt's Responsiveness Statistic (Rank) Standardized Response Mean (Rank) Median Rank
EQ5D–US Scoring 7 -0.45 (5) -0.18 (5) -0.18 (5) -0.22 (5) 5.00
EQ5D–UK Scoring 7 -0.06 (6) 0.00 (6) 0.00 (6) 0.00 (6) 6.00
EQ–VAS 7 -1.23 (4) -0.65 (1) -0.55 (3) -0.46 (4) 3.50
KCCQ Overall Summary Score 7 -1.56 (2) -0.34 (3) -0.71 (2) -0.59 (2) 2.00
KCCQ Clinical Summary Score 7 -1.88 (1) -0.32 (4) -0.72 (1) -0.71 (1) 1.00
RAND12 PCS Score 7 0.08 (7) 0.03 (7) 0.04 (7) 0.03 (7) 7.00
RAND12 MCS Score 7 -1.51 (3) -0.60 (2) -0.41 (4) -0.57 (3) 3.00
6 Minute Walk – Deteriorated -199 to -100       
EQ5D–US Scoring 16 0.59 (5) 0.08 (5) 0.18 (6) 0.17 (6) 5.50
EQ5D–UK Scoring 16 0.59 (5) 0.09 (6) 0.18 (5) 0.15 (5) 5.00
EQ–VAS 15 -1.44 (3) -0.31 (2) -0.49 (2) -0.37 (3) 2.50
KCCQ Overall Summary Score 16 -3.23 (1) -0.20 (3) -0.46 (3) -0.81 (1) 2.00
KCCQ Clinical Summary Score 16 -1.23 (4) -0.13 (4) -0.26 (4) -0.31 (4) 4.00
RAND12 PCS 16 1.74 (7) 0.20 (7) 0.38 (7) 0.43 (7) 7.00
RAND12 MCS 16 -2.30 (2) -0.62 (1) -0.95 (1) -0.58 (2) 1.50
6 Minute Walk – Deteriorated -99 to -25       
EQ5D–US Scoring 60 1.83 (6) 0.24 (7) 0.36 (7) 0.27 (7) 7.00
EQ5D–UK Scoring 60 1.83 (6) 0.23 (6) 0.35 (6) 0.26 (6) 6.00
EQ–VAS 58 0.92 (5) 0.12 (5) 0.13 (5) 0.12 (5) 5.00
KCCQ Overall Summary Score 60 0.04 (2) 0.00 (2) 0.01 (2) 0.01 (2) 2.00
KCCQ Clinical Summary Score 60 0.31 (3) 0.02 (3) 0.05 (3) 0.04 (3) 3.00
RAND12 PCS 60 0.51 (4) 0.04 (4) 0.07 (4) 0.07 (4) 4.00
RAND12 MCS 60 -0.73 (1) -0.06 (1) -0.09 (1) -0.09 (1) 1.00
6 Minute Walk – No Change -24 to 24       
EQ5D–US Scoring 114 0.58 0.00 0.00 0.00 -
EQ5D–UK Scoring 114 0.58 0.04 0.06 0.06 -
EQ–VAS 109 0.74 0.07 0.07 0.07 -
KCCQ Overall Summary Score 114 1.44 0.06 0.13 0.13 -
KCCQ Clinical Summary Score 114 0.59 0.03 0.06 0.06 -
RAND12 PCS 114 2.01 0.12 0.19 0.19 -
RAND12 MCS 114 0.24 0.02 0.02 0.02 -
6 Minute Walk – Improved +25 to +49       
EQ5D–US Scoring 33 1.66 (1) 0.25 (1) 0.36 (1) 0.31 (1) 1.00
EQ5D–UK Scoring 33 1.66 (1) 0.22 (2) 0.29 (2) 0.29 (2) 2.00
EQ–VAS 31 1.06 (3) 0.14 (3) 0.14 (3) 0.19 (3) 3.00
KCCQ Overall Summary Score 33 0.08 (5) 0.01 (5) 0.02 (5) 0.01 (5) 5.00
KCCQ Clinical Summary Score 33 -0.01 (6) 0.00 (6) 0.00 (6) 0.00 (6) 6.00
RAND12 PCS 33 -0.04 (7) -0.03 (7) -0.06 (7) -0.06 (7) 7.00
RAND12 MCS 33 0.85 (4) 0.09 (4) 0.13 (4) 0.15 (4) 4.00
6 Minute Walk – Improved +50 to +99       
EQ5D–US Scoring 40 2.10 (1) 0.28 (2) 0.45 (2) 0.36 (1) 1.50
EQ5D–UK Scoring 40 2.10 (1) 0.29 (1) 0.47 (1) 0.35 (2) 1.00
EQ–VAS 38 1.35 (5) 0.16 (4) 0.22 (5) 0.22 (5) 5.00
KCCQ Overall Summary Score 40 1.73 (4) 0.14 (5) 0.34 (4) 0.22 (4) 4.00
KCCQ Clinical Summary Score 40 1.92 (3) 0.16 (3) 0.36 (3) 0.30 (3) 3.00
RAND12 PCS 40 -0.20 (7) -0.02 (7) -0.04 (7) -0.03 (7) 7.00
RAND12 MCS 40 1.12 (6) 0.14 (6) 0.18 (6) 0.18 (6) 6.00
6 Minute Walk – Improved >= +100       
EQ5D–US Scoring 28 1.68 (4) 0.25 (4) 0.36 (4) 0.36 (4) 4.00
EQ5D–UK Scoring 28 1.68 (4) 0.21 (6) 0.29 (6) 0.31 (5) 5.50
EQ–VAS 27 1.93 (3) 0.26 (3) 0.33 (5) 0.37 (3) 3.00
KCCQ Overall Summary Score 28 3.87 (1) 0.48 (1) 0.94 (1) 0.73 (1) 1.00
KCCQ Clinical Summary Score 28 3.09 (2) 0.37 (2) 0.71 (2) 0.58 (2) 2.00
RAND12 PCS 28 1.48 (6) 0.23 (5) 0.43 (3) 0.28 (6) 5.50
RAND12 MCS 28 0.79 (7) 0.12 (7) 0.16 (7) 0.15 (7) 7.00