Table 8 Responsiveness statistics and relative ranking of selected HRQL measures according to change on the external criterion: Six-Minute Walk Test
6 Minute Walk – Deteriorated <= -200 | n | T-Statistic (Rank) | Effect Size (Rank) | Guyatt's Responsiveness Statistic (Rank) | Standardized Response Mean (Rank) | Median Rank |
|---|---|---|---|---|---|---|
EQ5D–US Scoring | 7 | -0.45 (5) | -0.18 (5) | -0.18 (5) | -0.22 (5) | 5.00 |
EQ5D–UK Scoring | 7 | -0.06 (6) | 0.00 (6) | 0.00 (6) | 0.00 (6) | 6.00 |
EQ–VAS | 7 | -1.23 (4) | -0.65 (1) | -0.55 (3) | -0.46 (4) | 3.50 |
KCCQ Overall Summary Score | 7 | -1.56 (2) | -0.34 (3) | -0.71 (2) | -0.59 (2) | 2.00 |
KCCQ Clinical Summary Score | 7 | -1.88 (1) | -0.32 (4) | -0.72 (1) | -0.71 (1) | 1.00 |
RAND12 PCS Score | 7 | 0.08 (7) | 0.03 (7) | 0.04 (7) | 0.03 (7) | 7.00 |
RAND12 MCS Score | 7 | -1.51 (3) | -0.60 (2) | -0.41 (4) | -0.57 (3) | 3.00 |
6 Minute Walk – Deteriorated -199 to -100 |  |  |  |  |  |  |
EQ5D–US Scoring | 16 | 0.59 (5) | 0.08 (5) | 0.18 (6) | 0.17 (6) | 5.50 |
EQ5D–UK Scoring | 16 | 0.59 (5) | 0.09 (6) | 0.18 (5) | 0.15 (5) | 5.00 |
EQ–VAS | 15 | -1.44 (3) | -0.31 (2) | -0.49 (2) | -0.37 (3) | 2.50 |
KCCQ Overall Summary Score | 16 | -3.23 (1) | -0.20 (3) | -0.46 (3) | -0.81 (1) | 2.00 |
KCCQ Clinical Summary Score | 16 | -1.23 (4) | -0.13 (4) | -0.26 (4) | -0.31 (4) | 4.00 |
RAND12 PCS | 16 | 1.74 (7) | 0.20 (7) | 0.38 (7) | 0.43 (7) | 7.00 |
RAND12 MCS | 16 | -2.30 (2) | -0.62 (1) | -0.95 (1) | -0.58 (2) | 1.50 |
6 Minute Walk – Deteriorated -99 to -25 |  |  |  |  |  |  |
EQ5D–US Scoring | 60 | 1.83 (6) | 0.24 (7) | 0.36 (7) | 0.27 (7) | 7.00 |
EQ5D–UK Scoring | 60 | 1.83 (6) | 0.23 (6) | 0.35 (6) | 0.26 (6) | 6.00 |
EQ–VAS | 58 | 0.92 (5) | 0.12 (5) | 0.13 (5) | 0.12 (5) | 5.00 |
KCCQ Overall Summary Score | 60 | 0.04 (2) | 0.00 (2) | 0.01 (2) | 0.01 (2) | 2.00 |
KCCQ Clinical Summary Score | 60 | 0.31 (3) | 0.02 (3) | 0.05 (3) | 0.04 (3) | 3.00 |
RAND12 PCS | 60 | 0.51 (4) | 0.04 (4) | 0.07 (4) | 0.07 (4) | 4.00 |
RAND12 MCS | 60 | -0.73 (1) | -0.06 (1) | -0.09 (1) | -0.09 (1) | 1.00 |
6 Minute Walk – No Change -24 to 24 |  |  |  |  |  |  |
EQ5D–US Scoring | 114 | 0.58 | 0.00 | 0.00 | 0.00 | - |
EQ5D–UK Scoring | 114 | 0.58 | 0.04 | 0.06 | 0.06 | - |
EQ–VAS | 109 | 0.74 | 0.07 | 0.07 | 0.07 | - |
KCCQ Overall Summary Score | 114 | 1.44 | 0.06 | 0.13 | 0.13 | - |
KCCQ Clinical Summary Score | 114 | 0.59 | 0.03 | 0.06 | 0.06 | - |
RAND12 PCS | 114 | 2.01 | 0.12 | 0.19 | 0.19 | - |
RAND12 MCS | 114 | 0.24 | 0.02 | 0.02 | 0.02 | - |
6 Minute Walk – Improved +25 to +49 |  |  |  |  |  |  |
EQ5D–US Scoring | 33 | 1.66 (1) | 0.25 (1) | 0.36 (1) | 0.31 (1) | 1.00 |
EQ5D–UK Scoring | 33 | 1.66 (1) | 0.22 (2) | 0.29 (2) | 0.29 (2) | 2.00 |
EQ–VAS | 31 | 1.06 (3) | 0.14 (3) | 0.14 (3) | 0.19 (3) | 3.00 |
KCCQ Overall Summary Score | 33 | 0.08 (5) | 0.01 (5) | 0.02 (5) | 0.01 (5) | 5.00 |
KCCQ Clinical Summary Score | 33 | -0.01 (6) | 0.00 (6) | 0.00 (6) | 0.00 (6) | 6.00 |
RAND12 PCS | 33 | -0.04 (7) | -0.03 (7) | -0.06 (7) | -0.06 (7) | 7.00 |
RAND12 MCS | 33 | 0.85 (4) | 0.09 (4) | 0.13 (4) | 0.15 (4) | 4.00 |
6 Minute Walk – Improved +50 to +99 |  |  |  |  |  |  |
EQ5D–US Scoring | 40 | 2.10 (1) | 0.28 (2) | 0.45 (2) | 0.36 (1) | 1.50 |
EQ5D–UK Scoring | 40 | 2.10 (1) | 0.29 (1) | 0.47 (1) | 0.35 (2) | 1.00 |
EQ–VAS | 38 | 1.35 (5) | 0.16 (4) | 0.22 (5) | 0.22 (5) | 5.00 |
KCCQ Overall Summary Score | 40 | 1.73 (4) | 0.14 (5) | 0.34 (4) | 0.22 (4) | 4.00 |
KCCQ Clinical Summary Score | 40 | 1.92 (3) | 0.16 (3) | 0.36 (3) | 0.30 (3) | 3.00 |
RAND12 PCS | 40 | -0.20 (7) | -0.02 (7) | -0.04 (7) | -0.03 (7) | 7.00 |
RAND12 MCS | 40 | 1.12 (6) | 0.14 (6) | 0.18 (6) | 0.18 (6) | 6.00 |
6 Minute Walk – Improved >= +100 |  |  |  |  |  |  |
EQ5D–US Scoring | 28 | 1.68 (4) | 0.25 (4) | 0.36 (4) | 0.36 (4) | 4.00 |
EQ5D–UK Scoring | 28 | 1.68 (4) | 0.21 (6) | 0.29 (6) | 0.31 (5) | 5.50 |
EQ–VAS | 27 | 1.93 (3) | 0.26 (3) | 0.33 (5) | 0.37 (3) | 3.00 |
KCCQ Overall Summary Score | 28 | 3.87 (1) | 0.48 (1) | 0.94 (1) | 0.73 (1) | 1.00 |
KCCQ Clinical Summary Score | 28 | 3.09 (2) | 0.37 (2) | 0.71 (2) | 0.58 (2) | 2.00 |
RAND12 PCS | 28 | 1.48 (6) | 0.23 (5) | 0.43 (3) | 0.28 (6) | 5.50 |
RAND12 MCS | 28 | 0.79 (7) | 0.12 (7) | 0.16 (7) | 0.15 (7) | 7.00 |