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Table 2 Paired t-tests comparing baseline and endpoint scores within each treatment group

From: Patient-reported outcomes in a trial of exenatide and insulin glargine for the treatment of type 2 diabetes

Health Outcomes Measure (mean, SD)

Exenatide

Insulin Glargine

 

Baseline

Endpoint

p value

Baseline

Endpoint

p value

DSC-R Overall Score

1.07 (0.83)

0.90 (0.80)

< 0.0001

0.99 (0.78)

0.84 (0.73)

0.0002

EQ-5D Index Score

0.82 (0.22)

0.85 (0.19)

0.08

0.84 (0.22)

0.87 (0.20)

0.049

Diabetes Treatment Flexibility Score

60.37 (22.24)

60.48 (22.33)

0.93

58.85 (22.81)

58.95 (23.37)

0.93

Diabetes Treatment Satisfaction Score

26.41 (7.00)

29.48 (6.12)

< 0.0001

26.31 (6.33)

30.04 (5.21)

< 0.0001

SF-36 Vitality Subscale Score

53.18 (20.87)

56.30 (20.58)

0.005

55.18 (21.35)

57.62 (20.37)

0.04

DSC-R Psychology: Fatigue Score

1.83 (1.26)

1.49 (1.21)

< 0.0001

1.60 (1.29)

1.34 (1.17)

0.0003

DSC-R Psychology: Cognitive Score

1.18 (1.12)

0.99 (1.08)

0.0006

1.14 (1.09)

0.91 (0.99)

0.0001

DSC-R Neurology: Pain Score

0.76 (0.98)

0.70 (0.99)

0.21

0.67 (0.90)

0.63 (0.92)

0.49

DSC-R Neurology: Sensory Score

0.91 (1.07)

0.83 (1.01)

0.10

0.77 (0.94)

0.78 (0.93)

0.83

DSC-R Cardiology Score

0.78 (0.89)

0.71 (0.86)

0.16

0.73 (0.86)

0.61 (0.80)

0.02

DSC-R Ophthalmology Score

0.79 (1.00)

0.62 (0.86)

0.003

0.79 (0.98)

0.64 (0.92)

0.006

DSC-R Hypoglycemia Score

1.09 (1.16)

0.94 (1.09)

0.03

1.10 (1.09)

0.93 (1.00)

0.009

DSC-R Hyperglycemia Score

1.47 (1.31)

1.07 (1.15)

< 0.0001

1.42 (1.25)

1.02 (1.13)

< 0.0001

DTSQ Frequency High Blood Sugar

3.61 (1.76)

2.19 (1.61)

< 0.0001

3.57 (1.67)

2.11 (1.45)

< 0.0001

DTSQ Frequency Low Blood Sugar

1.02 (1.37)

1.36 (1.56)

0.007

0.80 (1.21)

1.50 (1.43)

< 0.0001