Health Outcomes Measure (mean, SD) | Exenatide | Insulin Glargine | ||||
---|---|---|---|---|---|---|
 | Baseline | Endpoint | p value | Baseline | Endpoint | p value |
DSC-R Overall Score | 1.07 (0.83) | 0.90 (0.80) | < 0.0001 | 0.99 (0.78) | 0.84 (0.73) | 0.0002 |
EQ-5D Index Score | 0.82 (0.22) | 0.85 (0.19) | 0.08 | 0.84 (0.22) | 0.87 (0.20) | 0.049 |
Diabetes Treatment Flexibility Score | 60.37 (22.24) | 60.48 (22.33) | 0.93 | 58.85 (22.81) | 58.95 (23.37) | 0.93 |
Diabetes Treatment Satisfaction Score | 26.41 (7.00) | 29.48 (6.12) | < 0.0001 | 26.31 (6.33) | 30.04 (5.21) | < 0.0001 |
SF-36 Vitality Subscale Score | 53.18 (20.87) | 56.30 (20.58) | 0.005 | 55.18 (21.35) | 57.62 (20.37) | 0.04 |
DSC-R Psychology: Fatigue Score | 1.83 (1.26) | 1.49 (1.21) | < 0.0001 | 1.60 (1.29) | 1.34 (1.17) | 0.0003 |
DSC-R Psychology: Cognitive Score | 1.18 (1.12) | 0.99 (1.08) | 0.0006 | 1.14 (1.09) | 0.91 (0.99) | 0.0001 |
DSC-R Neurology: Pain Score | 0.76 (0.98) | 0.70 (0.99) | 0.21 | 0.67 (0.90) | 0.63 (0.92) | 0.49 |
DSC-R Neurology: Sensory Score | 0.91 (1.07) | 0.83 (1.01) | 0.10 | 0.77 (0.94) | 0.78 (0.93) | 0.83 |
DSC-R Cardiology Score | 0.78 (0.89) | 0.71 (0.86) | 0.16 | 0.73 (0.86) | 0.61 (0.80) | 0.02 |
DSC-R Ophthalmology Score | 0.79 (1.00) | 0.62 (0.86) | 0.003 | 0.79 (0.98) | 0.64 (0.92) | 0.006 |
DSC-R Hypoglycemia Score | 1.09 (1.16) | 0.94 (1.09) | 0.03 | 1.10 (1.09) | 0.93 (1.00) | 0.009 |
DSC-R Hyperglycemia Score | 1.47 (1.31) | 1.07 (1.15) | < 0.0001 | 1.42 (1.25) | 1.02 (1.13) | < 0.0001 |
DTSQ Frequency High Blood Sugar | 3.61 (1.76) | 2.19 (1.61) | < 0.0001 | 3.57 (1.67) | 2.11 (1.45) | < 0.0001 |
DTSQ Frequency Low Blood Sugar | 1.02 (1.37) | 1.36 (1.56) | 0.007 | 0.80 (1.21) | 1.50 (1.43) | < 0.0001 |