Table 1 Comparisons of clinical and physiological characteristics between women and men matched by their predicted FEV1
Clinical & Physiological Characteristics | Men (n = 73) | Women (n = 73) | p Value |
|---|---|---|---|
Age (years old) | 63 ± 8* | 56 ± 11* | <0.001 |
Age range | 47–77 | 37–79 | |
Pack-years history | 69 ± 26* | 47 ± 22* | <0.001 |
BMI (kg/m2) | 27 ± 4* | 25 ± 7* | 0.04 |
BMI ≤ 21(%) | 6 | 32 | 0.007 |
Charlson Index (points) | 3 (1–6) + | 1 (1–3) + | <0.001 |
MMRC (points) | |||
0–2 (%) | 93 | 71 | <0.001 |
3–4 (%) | 7 | 29 | |
Exacerbations in the last year | |||
Without admission | 0 (0–1) + | 1 (0–2) + | 0.013 |
With admission | 0 (0-0) + | 0 (0–1) + | 0.116 |
FRC % of predicted | 142 ± 31* | 134 ± 32* | 0.470 |
IC/TLC ≤ 0.25 (%) | 8 (11) | 7 (10) | 0.627 |
PaO2 (mmHg) | 70 ± 11* | 76 ± 11* | 0.004 |
PaCO2 (mmHg) | 45 ± 6* | 40 ± 5* | <0.001 |
6MWD (mts) | 529 ± 93* | 459 ± 79* | <0.001 |
6MWD % of Predictive | 107 ± 21* | 85 ± 17* | <0.05 |
SGRQ | |||
Total | 26 (15–52) + | 38 (30–47) + | 0.011 |
Symptoms | 39 (12–53) + | 48 (32–58) + | 0.028 |
Activity | 37 (14–62) + | 53 (40–62) + | 0.020 |
Impact | 15 (6–45) + | 28 (13–40) + | 0.013 |