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Table 4 Change in SF-36 norm based Domain scores in non-responders among refractory HCV patients re-treated with pegylated interferon alpha 2b and ribavirin

From: Improvement in quality of life measures in patients with refractory hepatitis C, responding to re-treatment with Pegylated interferon alpha -2b and ribavirin

SF-36 domain Change in scores compared to baseline at 48 wks to 24 wks (24 wk-48 wk)
  24 wks 48 wks 72 wks  
Physical Function -1.20 -1.37 1.36 0.62
Role-Physical -4.34 -5.49* -0.11 -1.16
Bodily Pain -3.73* -4.15* 1.32 -0.41
General Health -1.18 -3.03^ -1.36 -1.84
Vitality -3.47** -4.51* 2.05 -1.04
Social Functioning -3.42 -6.01* -0.22 -2.59
Role-Emotional -1.20 -4.42^^ -0.63 -2.42
Mental Health -1.85 -4.68* 0.58 -2.83
Physical Component Score -3.34* -2.83 1.08 0.51
Mental Component Score -2.13 -3.79* 0.19 -1.65
  1. * p = < .001 to .005, ** p = .006, ^ p = .02, ^^ p = .04. Negative value suggests a decrease in the QOL domain