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Table 4 Change in SF-36 norm based Domain scores in non-responders among refractory HCV patients re-treated with pegylated interferon alpha 2b and ribavirin

From: Improvement in quality of life measures in patients with refractory hepatitis C, responding to re-treatment with Pegylated interferon alpha -2b and ribavirin

SF-36 domain

Change in scores compared to baseline at

48 wks to 24 wks (24 wk-48 wk)

 

24 wks

48 wks

72 wks

 

Physical Function

-1.20

-1.37

1.36

0.62

Role-Physical

-4.34

-5.49*

-0.11

-1.16

Bodily Pain

-3.73*

-4.15*

1.32

-0.41

General Health

-1.18

-3.03^

-1.36

-1.84

Vitality

-3.47**

-4.51*

2.05

-1.04

Social Functioning

-3.42

-6.01*

-0.22

-2.59

Role-Emotional

-1.20

-4.42^^

-0.63

-2.42

Mental Health

-1.85

-4.68*

0.58

-2.83

Physical Component Score

-3.34*

-2.83

1.08

0.51

Mental Component Score

-2.13

-3.79*

0.19

-1.65

  1. * p = < .001 to .005, ** p = .006, ^ p = .02, ^^ p = .04. Negative value suggests a decrease in the QOL domain