Parsimonious and efficient assessment of health-related quality of life in osteoarthritis research: validation of the Assessment of Quality of Life (AQoL) instrument

Whitfield, Kathryn; Buchbinder, Rachelle; Segal, Leonie; Osborne, Richard H

doi:10.1186/1477-7525-4-19

Table 5 Ability of the Instruments to discriminate between individuals on the basis of self-rated health

From: Parsimonious and efficient assessment of health-related quality of life in osteoarthritis research: validation of the Assessment of Quality of Life (AQoL) instrument

	Self-rated General Health				Comparison of Means				ROC			Absolute Performance Gain
Instruments	Poor health (n = 54)		Good health (n = 168)		Effect size #	SD.	t	RE	Area Under Curve	Asymptotic 95% CI		Z	APG %	95% CI
	M	SD.	M	SD.						Lower	Upper			Lower	Upper
AQOL
Utility Score	0.32	0.20	0.52	0.21	-1.00	0.20	-6.4	1.00	**0.76	0.69	0.83	Reference
Independent living	0.67	0.22	0.80	0.19	-0.69	0.20	-4.4	0.48	**0.68	0.60	0.77	1.05	15.8	1.1	30.4
Social relationships	0.76	0.21	0.85	0.17	-0.53	0.18	-3.4	0.29	**0.67	0.59	0.75	1.14	17.8	2.4	33.1
Physical senses	0.89	0.10	0.91	0.09	-0.23	0.09	-1.4	0.05	0.56	0.47	0.64	^2.06	40.6	21.3	59.9
Psychological wellbeing	0.66	0.17	0.80	0.13	-0.98	0.14	-6.3	0.97	**0.79	0.72	0.86	-0.38	5.7	-9.2	20.7
SF-36
Physical function	26.6	17.7	40.8	22.4	-0.66	21.4	-4.3	0.44	**0.69	0.62	0.77	0.79	14.0	-3.4	31.3
Role physical	5.6	15.1	31.1	38.8	-0.74	34.6	-4.7	0.55	**0.69	0.61	0.76	0.79	15.1	-3.7	34.0
Bodily pain	24.8	14.0	43.7	18.1	-1.10	17.2	-7.0	1.21	**0.80	0.73	0.87	-0.46	7.4	-8.4	23.3
Vitality	28.8	18.0	50.3	19.5	-1.12	19.2	-7.2	1.26	**0.78	0.72	0.85	-0.25	4.2	-12.5	21.0
Social function	51.9	21.5	69.8	27.1	-0.69	25.8	-4.4	0.48	**0.70	0.63	0.78	0.71	11.4	-4.4	27.2
Role emotional	24.7	39.0	64.0	42.7	-0.94	41.8	-6.0	0.89	**0.73	0.66	0.81	0.28	5.4	-13.2	23.9
Mental health	54.7	17.4	70.6	18.7	-0.86	18.4	-5.5	0.75	**0.74	0.67	0.81	0.25	4.3	-12.8	21.4
PCS	25.3	5.6	32.4	9.2	-0.84	8.5	-5.4	0.71	**0.74	0.67	0.81	0.26	4.9	-1.4	23.4
WOMAC
Pain	57.6	17.9	41.8	20.2	0.81	19.7	5.2	0.65	**0.73	0.65	0.80	0.41	7.2	-10.1	24.5
Stiffness	64.8	18.0	49.0	18.8	0.85	18.6	5.4	0.72	**0.72	0.65	0.80	0.41	7.6	-10.4	25.6
Physical function	59.6	15.5	43.1	19.7	0.88	18.8	5.6	0.77	**0.74	0.67	0.81	0.23	3.9	-12.5	20.4
WOMAC score	59.6	15.0	43.3	18.5	0.92	17.6	5.9	0.84	**0.75	0.68	0.82	0.13	2.1	-14.3	18.5
VAS (over past week)
Average pain	-62.3	21.0	-46.4	23.2	-0.70	22.7	-4.5	0.49	**0.69	0.61	0.77	0.75	13.6	-4.3	31.4
Pain at rest	-45.3	21.7	-28.0	21.8	-0.79	21.8	-5.1	0.63	**0.72	0.65	0.80	0.43	7.8	-10.0	25.7
ADL Restriction	-54.7	23.5	-39.6	25.5	-0.60	25.1	-3.8	0.36	**0.66	0.59	0.74	1.11	19.4	2.3	36.6

N = 222, * All significant < 0.001 except Physical senses, p = 0.15.
^#Note: For the effect size calculations the poor health group was nominated as the 'control group'.

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ISSN: 1477-7525

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