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Table 2 Summary of studies using the SF-36 to assess quality of life in patients with bipolar disorder1

From: Quality of life in bipolar disorder: A review of the literature

Study Patient population Physical Social Role physical Role emotional Pain Mental health General health Vitality
Arnold (2000) 44 BD outpatients 78.8 ± 22.4 57.9 ± 27.7 63.1 ± 41.6 38.6 ± 43.1 64.9 ± 25.7 55.3 ± 23.8 61.9 ± 25.4 43.6 ± 24.3
Have (2002)2 93 BD type I
43 BD NOS
89.6
91.2
73.6
80.8
77.6
81.7
69.5
80.6
74.1
82.5
62.3
68.7
62.6
68.2
58.0
62.0
Leidy (1998) 34 euthymic
28 depressed
84.4 ± 20.2
72.2 ± 28.3
73.2 ± 18.2
29.3 ± 20.0
86.2 ± 28.0
32.3 ± 38.6
76.2 ± 31.2
8.3 ± 20.3
59.6 ± 29.0
54.7 ± 25.3
69.2 ± 17.9
33.4 ± 16.5
70.9 ± 20.7
58.0 ± 21.2
52.0 ± 16.2
20.4 ± 17.5
Namjoshi (2002) 122 BD type I (manic/mixed) 65 olanzapine 57 placebo 86.8 ± 16.8
84.5 ± 21.9
47.1 ± 28.3
46.0 ± 31.8
70.4 ± 40.2
65.4 ± 40.3
37.4 ± 42.3
36.3 ± 43.3
68.4 ± 26.4
61.7 ± 25.0
59.9 ± 22.6
58.5 ± 19.8
69.0 ± 22.7
65.2 ± 24.3
63.3 ± 24.0
66.6 ± 20.0
Patelis-Siotis (2001) 34 BD CBT completers
8 BD CBT non-completers
80.4 ± 19.3
63.8 ± 30.6
58.1 ± 25.0
46.9 ± 28.1
41.2 ± 39.8
40.6 ± 44.2
17.6 ± 33.1
29.2 ± 41.5
68.5 ± 23.7
63.4 ± 27.0
52.4 ± 18.0
44.0 ± 22.0
66.6 ± 21.7
46.4 ± 29.6
39.4 ± 19.3
28.1 ± 21.4
Revicki (1997) 14 BD patients (in-person)
14 BD patients (by telephone)
78.4 ± 25.2
77.0 ± 29.3
53.6 ± 30.2
57.1 ± 29.9
65.2 ± 38.7
59.8 ± 41.0
40.5 ± 42.9
33.3 ± 40.6
68.0 ± 31.8
69.3 ± 28.2
53.4 ± 22.8
53.9 ± 20.0
59.8 ± 22.8
57.5 ± 22.7
41.4 ± 18.7
41.4 ± 20.5
Tsevat (2000) 53 BD patients 78.7 ± 23.4 58.7 ± 27.9 63.2 ± 40.9 38.9 ± 42.3 65.3 ± 26.0 56.2 ± 23.7 62.1 ± 24.3 45.4 ± 24.4
Shi (2002) 453 BD type I
234 olanzapine 219 haloperidol
85.2 ± 23.2
90.5 ± 15.7
61.1 ± 31.8
61.2 ± 29.1
66.1 ± 39.6
72.8 ± 36.3
53.3 ± 43.1
50.1 ± 43.7
79.8 ± 26.2
81.2 ± 26.1
71.0 ± 20.4
72.8 ± 16.5
73.6 ± 21.8
75.1 ± 19.2
75.8 ± 19.1
80.0 ± 14.9
Shi (2004) 573 BD type I (currently depressed)
250 olanzapine
58 olanzapine/fluoxetine combination
265 placebo
65.8 ± 27.6
68.8 ± 25.0
66.6 ± 26.2
29.1 ± 20.9
30.6 ± 20.8
32.5 ± 21.4
47.8 ± 44.0
44.8 ± 41.8
46.4 ± 42.3
12.9 ± 25.4
9.8 ± 23.4
14.6 ± 28.7
60.6 ± 27.1
60.8 ± 25.6
57.8 ± 26.1
30.0 ± 16.1
31.0 ± 17.3
31.3 ± 15.7
51.1 ± 22.3
52.3 ± 20.7
48.6 ± 22.6
25.5 ± 17.5
25.3 ± 19.0
25.6 ± 17.6
Yatham (2004) 920 BD type I (currently depressed/ depressive episode in previous 60 days) 70.2 ± 26.2 29.9 ± 22.8 36.7 ± 40.9 11.4 ± 23.5 62.2 ± 27.1 31.0 ± 17.3 47.5 ± 23.3 22.4 ± 17.7
  1. 1 Data presented as mean ± SD
  2. 2 SDs not available