Evaluating change in health-related quality of life in adult rhinitis: Responsiveness of the Rhinosinusitis Disability Index

Table 4 Relationship between change in RSDI and change in rhinitis-specific health outcomes

		Change in RSDI as a predictor of change in health outcome
		Unadjusted model			Adjusted model
Dependent variable	Mean change ± SD	β	± SE	p value	β	± SE	p value
Restricted activity (days per month)	2.4 ± 7.3	2.48	± 0.84	<0.01	2.48	± 0.98	0.01
Job effectiveness* (% effectiveness)	-2.4 ± 12.8	-4.78	± 2.03	0.02	-4.27	± 1.95	0.03
Physician visits (# of visits per yr)	-0.1 ± 3.1	0.41	± 0.46	0.38	0.36	± 0.47	0.45
Cost of medications ($ per year)	4.9 ± 309	87.44	± 36.16	0.02	78.52	± 38.73	0.05

Effect estimates are reported per 1.0 SRM change in the RSDI score. Adjusted model includes baseline symptom severity (RSS-4), physical functioning (SF-12 PCS), psychological distress (CES-D), and perceived control of disease (PCRQ). * Data not available for 24 subjects (9 unemployed, 11 house keeping, 2 attending school, 1 retired, 1 other).

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