Evaluating change in health-related quality of life in adult rhinitis: Responsiveness of the Rhinosinusitis Disability Index

Table 2 Change in health-related quality of life and health status among 69 adults with rhinitis

Measure	Baseline (mean ± SD)	24 month follow-up (mean ± SD)	Observed change* (mean ± SE)	Standardized response mean^†	p value^‡
RSDI – Total	23.3 ± 23.4	24.6 ± 24.0	1.3 ± 2.7	0.06	0.63
Physical	11.2 ± 10.6	10.7 ± 9.6	-0.4 ± 1.2	-0.04	0.72
Functional	5.6 ± 7.0	6.5 ± 7.5	0.9 ± 0.9	0.13	0.28
Emotional	6.6 ± 7.7	7.3 ± 8.4	0.8 ± 1.0	0.10	0.42
RSS-4	6.9 ± 4.6	5.4 ± 3.9	-1.5 ± 0.5	-0.31	0.01
CES-D	10.5 ± 10	11.5 ± 9.9	1.0 ± 1.3	0.09	0.43
SF-12 PCS	48.2 ± 8.6	47.8 ± 9.0	-0.5 ± 1.0	-0.05	0.65
PCRQ	27.7 ± 4.8	28.8 ± 5.2	1.2 ± 0.7	0.21	0.09

RSDI = Rhinosinusitis Disability Index; RSS-4 = 4-item Rhinitis Symptom Score; CES-D = Center for Epidemiologic Studies Depression scale; SF-12 PCS = Short Form 12 Physical Component Summary; PCRQ = Perceived Control of Rhinitis Questionnaire. * Observed change = (score at follow-up) - (score at baseline). † Standardized response mean = [(score at follow-up) - (score at baseline)/(SD of observed change)]. ‡ Paired t test

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