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Table 2 The effect of demographic characteristics on clinically relevant variation in function over two years

From: The effect of patient characteristics on variability in pain and function over two years in early knee osteoarthritis

 

KOOS Activities of Daily Living

SF-36 Physical Function

Characteristic

Prevalence of clinically relevant change

Unadjusted for baseline values

Adjusted for baseline values

Prevalence of clinically relevant change

Unadjusted for baseline values

Adjusted for baseline value

 

N

%

OR

OR

95% CI

N

%

OR

OR

95% CI

Age

   <46†

6/49

12

   

21/49

43

   

   46–56

19/47

40

4.5

3.8

1.2–12.4

24/45

53

1.2

0.9

0.3–2.4

   >56

13/47

28

2.5

1.8

0.5–6.2

23/46

50

1.3

0.5

0.2–1.4

Gender

   men†

32/120

27

   

54/118

46

   

   women

6/23

26

1.2

0.7

0.2–2.3

14/22

64

2.4

1.9

0.6–6.1

BMI (kg/m2)

   <25†

9/61

15

   

21/60

35

   

   25–29.9

22/64

34

1.4

2.0

0.5–3.9

39/63

62

3.2

2.4

1.0–5.7

   ≥30

7/16

44

1.4

1.8

0.3–6.3

6/15

40

1.2

0.1

0.2–0.9

  1. KOOS = Knee injury and Osteoarthritis Outcome Score, OR = odds ratio, 95% CI = 95% confidence interval, BMI = body mass index.
  2. * All risk factors listed are entered simultaneously in each model.
  3. † Reference category.