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Table 4 Results of regression of SCD-specific variables on SF-36 subscales, controlling for socio-demographic variables1 (regression coefficients ± standard error)

From: Health related quality of life in sickle cell patients: The PiSCES project

 

Genotype2

Mean pain

Proportion Days with Crisis3

Proportion Days with Utilization4

Physical Function

-5.01 ± 3.30

-4.55 ± 0.72**

-0.42 ± 2.12

3.51 ± 1.97

Role-Physical

-1.62 ± 5.73

-6.12 ± 1.27**

-0.91 ± 3.70

2.75 ± 3.39

Bodily Pain

0.14 ± 3.57

-4.41 ± 0.79**

-5.93 ± 2.31*

-0.59 ± 2.13

General Health

3.52 ± 3.19

-3.34 ± 0.71**

-1.31 ± 2.09

-1.44 ± 1.92

Vitality

6.43 ± 3.27*

-3.54 ± 0.72**

0.55 ± 2.10

3.06 ± 1.94

Social Function

3.16 ± 3.77

-4.27 ± 0.82**

-3.28 ± 2.44

1.93 ± 2.25

Role-emotional

7.06 ± 6.27

-5.81 ± 1.39**

2.30 ± 4.09

2.12 ± 3.71

Mental Health

4.23 ± 3.14

-1.44 ± 0.69*

-1.53 ± 2.02

0.35 ± 1.87

  1. 1controlling for age, gender, years of education
  2. 2SS and Sßo Thalasemia vs SC and Sß+ Thalasemia
  3. 3Percent of days with crises: 0, 0.1–10,10+ (coded 1,2,3)
  4. 4Percent of days with utilization: 0, 0.1–3, 3+ (coded 1,2,3)
  5. *p ≤ 0.05; **p < 0.0001