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Table 4 Results of regression of SCD-specific variables on SF-36 subscales, controlling for socio-demographic variables1 (regression coefficients ± standard error)

From: Health related quality of life in sickle cell patients: The PiSCES project

  Genotype2 Mean pain Proportion Days with Crisis3 Proportion Days with Utilization4
Physical Function -5.01 ± 3.30 -4.55 ± 0.72** -0.42 ± 2.12 3.51 ± 1.97
Role-Physical -1.62 ± 5.73 -6.12 ± 1.27** -0.91 ± 3.70 2.75 ± 3.39
Bodily Pain 0.14 ± 3.57 -4.41 ± 0.79** -5.93 ± 2.31* -0.59 ± 2.13
General Health 3.52 ± 3.19 -3.34 ± 0.71** -1.31 ± 2.09 -1.44 ± 1.92
Vitality 6.43 ± 3.27* -3.54 ± 0.72** 0.55 ± 2.10 3.06 ± 1.94
Social Function 3.16 ± 3.77 -4.27 ± 0.82** -3.28 ± 2.44 1.93 ± 2.25
Role-emotional 7.06 ± 6.27 -5.81 ± 1.39** 2.30 ± 4.09 2.12 ± 3.71
Mental Health 4.23 ± 3.14 -1.44 ± 0.69* -1.53 ± 2.02 0.35 ± 1.87
  1. 1controlling for age, gender, years of education
  2. 2SS and Sßo Thalasemia vs SC and Sß+ Thalasemia
  3. 3Percent of days with crises: 0, 0.1–10,10+ (coded 1,2,3)
  4. 4Percent of days with utilization: 0, 0.1–3, 3+ (coded 1,2,3)
  5. *p ≤ 0.05; **p < 0.0001