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Table 2 Baseline Costs for a Pharmacoeconomic Model of Vasomotor Symptoms

From: Psychosocial and socioeconomic burden of vasomotor symptoms in menopause: A comprehensive review

Drug acquisition costs  
   Norethindrone acetate/ethinyl estradiol $357
   Conjugated estrogen/medroxyprogesterone $474
Therapy initiation  
   Two physician visits $132
Breakthrough bleeding at 3 months (or continued spotting at 6 months)  
   Endometrial biopsy $198
   Pathology and laboratory fees $147
Telephone call to physician  
   Spotting at 3 months $16
Moderate to severe vasomotor symptoms  
   Two physician visits $132
   90-day supply of clonidine $31
  1. Adapted with permission from Botteman et al. [45].